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Pharmacological activity of the dinitrate metabolites of nitroglycerin following their oral administration to healthy volunteers.

作者信息

Gumbleton M, Benet L Z

出版信息

Br J Clin Pharmacol. 1991 Feb;31(2):211-3. doi: 10.1111/j.1365-2125.1991.tb05521.x.

DOI:10.1111/j.1365-2125.1991.tb05521.x
PMID:1904752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1368399/
Abstract
摘要

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本文引用的文献

1
Pharmacokinetics of nitroglycerin and metabolites in humans following oral dosing.口服给药后人体中硝酸甘油及其代谢产物的药代动力学。
Biopharm Drug Dispos. 1988 Nov-Dec;9(6):557-65. doi: 10.1002/bod.2510090606.
2
Variable glyceryl dinitrate formation as a function of route of nitroglycerin administration.
Clin Pharmacol Ther. 1987 Sep;42(3):273-7. doi: 10.1038/clpt.1987.146.
3
The bioavailability of oral nitroglycerin.
J Pharm Sci. 1986 Mar;75(3):241-3. doi: 10.1002/jps.2600750306.
4
Pharmacokinetics of nitroglycerin and its dinitrate metabolites over a thirtyfold range of oral doses.硝酸甘油及其二硝酸盐代谢产物在三十倍口服剂量范围内的药代动力学。
Clin Pharmacol Ther. 1990 May;47(5):592-8. doi: 10.1038/clpt.1990.80.
5
Oral nitroglycerin as a prophylactic antianginal drug: clinical, physiologic, and statistical evidence of efficacy based on a three-phase experimental design.
Am Heart J. 1975 Nov;90(5):611-26. doi: 10.1016/0002-8703(75)90226-4.
6
Effect of sustained release nitroglycerin capsules on anginal frequency and exercise capacity: a double-blind evaluation.
Angiology. 1977 Mar;28(3):181-9. doi: 10.1177/000331977702800306.