Lihonenko O V, Dihtiar I I
Klin Khir. 2008 Jul(7):55-8.
Estrogens and liposomes positively influence current wounds healing. But a degree of their influence as separately, and in a combination with each other, on current of purulent wounds are investigated insufficiently. The purpose of research--to estimate dynamics of current of experimental purulent wounds of soft fabrics at use in complex treatment estrogens and liposomes. Modelled a purulent wound. All animals treated according to standard techniques. An animal of the first group to complex treatment added estrogens, the second--liposomes, the third--simultaneously estrogens and liposomes. Determined a level oxyproline, RNA, DNA, index RNA/DNA in wounds. Use in complex treatment of purulent wounds estrogens and liposomes leads to increase in synthesis of collagen, increase of biosynthetic activity and repair processes in the field of a wound in the second and a third phase of current wounds process which are more expressed at their combined application.
雌激素和脂质体对当前伤口愈合有积极影响。但它们各自以及相互结合对脓性伤口愈合的影响程度尚未得到充分研究。本研究的目的是评估在复合治疗中使用雌激素和脂质体时，软组织实验性脓性伤口愈合的动态变化。模拟了脓性伤口。所有动物均按照标准技术进行治疗。第一组动物在复合治疗中添加雌激素，第二组添加脂质体，第三组同时添加雌激素和脂质体。测定伤口中羟脯氨酸、RNA、DNA水平以及RNA/DNA指数。在脓性伤口的复合治疗中使用雌激素和脂质体可导致胶原蛋白合成增加，在伤口愈合过程的第二和第三阶段，伤口部位的生物合成活性和修复过程增强，且在联合应用时更为明显。
