Freeman Ronit, Willner Itamar
Institute of Chemistry and the Farkas Center for Light-Induced Processes, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Nano Lett. 2009 Jan;9(1):322-6. doi: 10.1021/nl8030532.
Phenyl boronic acid-functionalized CdSe/ZnS quantum dots (QDs) were synthesized. The modified particles bind nicotinamide adenine dinucleotide (NAD(+)) or 1,4-dihydronicotinamide adenine dinucleotide (NADH). The NAD(+)-functionalized QDs are effectively quenched by an electron transfer process, while the NADH-modified QDs are inefficiently quenched by the reduced cofactor. These properties enable the implementation of the QDs for the fluorescence analysis of ethanol in the presence of alcohol dehydrogenase. The NADH-functionalized QDs were used for the optical analysis of the 1,3,5-trinitrotriazine, RDX explosive, with a detection limit that corresponded to 1 x 10(-10) M. We demonstrate cooperative optical and catalytic functions of the core-shell components of the QDs in the analysis of RDX.
合成了苯基硼酸功能化的CdSe/ZnS量子点（QDs）。修饰后的颗粒可结合烟酰胺腺嘌呤二核苷酸（NAD(+)）或1,4 - 二氢烟酰胺腺嘌呤二核苷酸（NADH）。NAD(+)功能化的量子点通过电子转移过程被有效猝灭，而NADH修饰的量子点被还原辅因子猝灭的效率较低。这些特性使得量子点能够用于在乙醇脱氢酶存在下对乙醇进行荧光分析。NADH功能化的量子点用于1,3,5 - 三硝基三嗪（RDX炸药）的光学分析，检测限为1×10(-10) M。我们展示了量子点的核壳组件在RDX分析中的协同光学和催化功能。
