van 't Riet E, Alssema M, Nijpels G, Dekker J M
VU Medisch Centrum, EMGO Instituut, Van der Boechorststraat 7, kamer D-528, io8x BT Amsterdam.
Ned Tijdschr Geneeskd. 2008 Nov 1;152(44):2385-8.
Overweight (BMI level > or =25 kg/m2) and in particular high abdominal fat levels (waist circumference > or =88 cm in women and > or =102 cm in men), are among the main risk factors for the development of type 2 diabetes mellitus. Results from the Hoorn Study show that 16.3% of overweight participants with high abdominal fat levels developed diabetes within 6 years, compared with 6.8% of those who were not overweight and had low abdominal fat levels. Information on overweight and abdominal fat level is not enough to properly estimate the risk of type 2 diabetes in an individual patient. The combination of information on overweight with information on other important risk factors for diabetes, such as family history, age, blood pressure and elevated blood glucose levels in the form of a calculated diabetes risk score, gives a better estimate of the individual diabetes risk.
超重(体重指数水平≥25千克/平方米),尤其是腹部脂肪水平高(女性腰围≥88厘米,男性腰围≥102厘米),是2型糖尿病发生的主要风险因素。霍恩研究的结果表明,腹部脂肪水平高的超重参与者中有16.3%在6年内患上糖尿病,相比之下,非超重且腹部脂肪水平低的参与者这一比例为6.8%。关于超重和腹部脂肪水平的信息不足以准确估计个体患者患2型糖尿病的风险。将超重信息与糖尿病其他重要风险因素的信息(如家族史、年龄、血压以及以计算得出的糖尿病风险评分形式表示的血糖水平升高)相结合,能更好地估计个体患糖尿病的风险。