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[不同类型甲状腺肿中某些氧化还原水解酶的组织化学特征]

[Histochemical characteristics of some oxidation-reduction hydrolytic enzymes in different forms of goiter].

作者信息

Kasab'ian S S, Pisarev V B

出版信息

Probl Endokrinol (Mosk). 1976 Nov-Dec;22(6):26-9.

PMID:190604
Abstract

Histochemical study of some enzymatic systems was conducted in various form of goiter. A study was made of the thyroid gland tissue obtained during the operation in 96 patients. Euthyrosis was accompanied by a decrease in the succinic dehydrogenase, cytochromoxidase, iodide peroxidase, acid and alkaline phosphatase activity. As to thyrotoxic goiter - it displayed an increase in the activity of these enzymes and desquamation of the follicular epithelium; the rejected cells possessed a high acid phosphatase activity. In comparison with thyrotoxic goiter, Askinazi's cell count was increased in the euthyroid macrofollicular nodular and diffuse goiter.

摘要

对各种类型甲状腺肿的一些酶系统进行了组织化学研究。对96例患者手术中获取的甲状腺组织进行了研究。甲状腺功能正常伴随着琥珀酸脱氢酶、细胞色素氧化酶、碘过氧化物酶、酸性和碱性磷酸酶活性的降低。至于甲状腺毒症性甲状腺肿,这些酶的活性增加,滤泡上皮细胞脱屑;脱落的细胞具有高酸性磷酸酶活性。与甲状腺毒症性甲状腺肿相比,甲状腺功能正常的大滤泡性结节性和弥漫性甲状腺肿中Askinazi细胞计数增加。

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