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类固醇与拔管:临床试验的可能性。

Steroids and extubation: the potential for clinical trials.

作者信息

Greenhalgh David G

机构信息

Shriners Hospitals for Children, Northern California, USA.

出版信息

J Burn Care Res. 2009 Jan-Feb;30(1):196-7. doi: 10.1097/BCR.0b013e3181923f28.

DOI:10.1097/BCR.0b013e3181923f28
PMID:19060752
Abstract

Intubation and mechanical ventilation are necessary adjuncts to airway management of the patient with inhalation injury. However, the ultimate goal of intubation is ultimate removal from mechanical ventilation. Extubation of the inhalation injury patient is often challenging due to the increased work of breathing, multiple operative interventions, and increased metabolic rate that often accompanies inhalation injury. The next two papers in the compendium describe two very different, yet potentially applicable, adjuncts to extubation of the burn patient: steroids and noninvasive positive pressure ventilation.

摘要

气管插管和机械通气是吸入性损伤患者气道管理的必要辅助手段。然而,气管插管的最终目标是最终脱离机械通气。由于呼吸功增加、多次手术干预以及吸入性损伤常伴随的代谢率升高,吸入性损伤患者的拔管往往具有挑战性。该论文集接下来的两篇论文描述了两种截然不同但可能适用的烧伤患者拔管辅助手段:类固醇和无创正压通气。

相似文献

1
Steroids and extubation: the potential for clinical trials.类固醇与拔管:临床试验的可能性。
J Burn Care Res. 2009 Jan-Feb;30(1):196-7. doi: 10.1097/BCR.0b013e3181923f28.
2
Potential studies in extubation adjuncts after inhalation injury.吸入性损伤后拔管辅助手段的潜在研究。
J Burn Care Res. 2009 Jan-Feb;30(1):199-200. doi: 10.1097/BCR.0b013e3181923f48.
3
Noninvasive positive pressure ventilation as an adjunct to extubation in the burn patient.无创正压通气作为烧伤患者拔管的辅助手段。
J Burn Care Res. 2009 Jan-Feb;30(1):198-9. doi: 10.1097/BCR.0b013e3181923f38.
4
Brother, have you got a light? Assessing the need for intubation in patients sustaining burn injury secondary to home oxygen therapy.兄弟,有火吗?评估家庭氧疗继发烧伤患者的插管需求。
J Burn Care Res. 2012 Nov-Dec;33(6):e280-5. doi: 10.1097/BCR.0b013e31824d1b3c.
5
Inhalation injury and endotracheal intubation.
J Burn Care Res. 2009 Jan-Feb;30(1):190-1. doi: 10.1097/BCR.0b013e3181923eb4.
6
A survey of airway and ventilator management strategies in North American pediatric burn units.北美儿科烧伤病房气道与呼吸机管理策略调查
J Burn Care Rehabil. 2004 Sep-Oct;25(5):435-40. doi: 10.1097/01.bcr.0000138294.39313.6b.
7
Respiratory care of the burn patient.烧伤患者的呼吸护理。
J Burn Care Rehabil. 2005 May-Jun;26(3):200-6.
8
Prophylactic administration of parenteral steroids for preventing airway complications after extubation in adults: meta-analysis of randomised placebo controlled trials.成人拔管后预防气道并发症的肠外类固醇预防性给药:随机安慰剂对照试验的荟萃分析
BMJ. 2008 Oct 20;337:a1841. doi: 10.1136/bmj.a1841.
9
[Prognostic criteria of the premature infants weaning from mechanical ventilation during trigger ventilation].[触发通气期间早产儿机械通气撤机的预后标准]
Anesteziol Reanimatol. 2013 Jan-Feb(1):26-30.
10
Discontinuing mechanical ventilatory support: removing positive pressure ventilation vs removing the artificial airway.停止机械通气支持:撤除正压通气与拔除人工气道
Chest. 2006 Dec;130(6):1635-6. doi: 10.1378/chest.130.6.1635.