Alhasan S U, Aji S A, Mohammed A Z, Malami S
Department of Surgery, Bayero University and Aminu Kano Teaching Hospital, PMB 3452, Kano, Nigeria.
BMC Urol. 2008 Dec 6;8:18. doi: 10.1186/1471-2490-8-18.
Benign prostatic hyperplasia (BPH) is the commonest disease of the urinary tract afflicting the ageing male and is the commonest neoplastic disease in men aged 50 years and above. Transurethral prostatectomy (TURP) is the ultimate treatment of choice for benign prostatic hyperplasia (BPH) due mainly to the preference of minimally invasive surgery, long term relief of symptoms and cost effectiveness. It is however not available to the majority of Nigerians in need of prostatic surgery in Public Health Institutions.
The records of patients who underwent prostatectomy in Aminu Kano Teaching Hospital, over the period June 2001 to July 2007 were examined. The bio data of patients and laboratory investigations performed were retrieved.
Five Hundred and forty two patients were operated upon, out of which 40 were excluded due to open prostatectomy (22 patients), bladder neck stenosis (16 patients) or bladder tumour around the trigon (2 patients). The age range of the patients was 47-110 years with a mean of 67.2 years. 289 patients (80.1%) had urethral catheter in situ at presentation and 11 (3%) patients had suprapubic cystostomy of which only 3 (0.85%) had combined urethral stricture and BPH. Only 131 (26%) had their PSA measured which ranged from 2-100 ng/ml out of which 39(29.8% n = 131) patients had more than 4 ng/ml and cancer of the prostate and 1(0.8%, n = 131) patient had a PSA level of 4 ng/ml and malignant prostate. Hospital stay was 1-32 days (mean 7.9) and the mean follow up period was 5.6 months (range 0-60) and there were 17.5% complications comprising of urinary tract infection (UTI) 7.2%, Orchitis 2.2%, urinary incontinence 0.6%, atonic bladder 1%, erectile dysfunction 0.6%, cerebrovascular accident 0.4%, myocardial infarction 0.4%, deep vein thrombosis 0.4% and disseminated intravascular coagulopathy (DIC) 0.6% and 1.2% mortality. The cost of treatment inclusive of pre-admission investigations was US$ 615.00 (range US$ 300-1,300)
Despite advances in minimally invasive therapy for LUTH/BPH, TURP is the optimum treatment of choice for the ageing male of sub-Saharan Africa. It is however not available to the majority of patients in this region due to poor health allocation and inadequate facilities and training.
良性前列腺增生(BPH)是困扰老年男性的最常见泌尿系统疾病,也是50岁及以上男性中最常见的肿瘤性疾病。经尿道前列腺切除术(TURP)主要由于其微创手术的优势、症状的长期缓解以及成本效益,是良性前列腺增生(BPH)的最终治疗选择。然而,大多数需要前列腺手术的尼日利亚人在公共卫生机构无法获得这种治疗。
检查了2001年6月至2007年7月期间在阿明努·卡诺教学医院接受前列腺切除术的患者记录。检索了患者的生物数据和进行的实验室检查。
542例患者接受了手术,其中40例因开放性前列腺切除术(22例患者)、膀胱颈狭窄(16例患者)或膀胱三角区周围膀胱肿瘤(2例患者)被排除。患者年龄范围为47 - 110岁,平均年龄为67.2岁。289例患者(80.1%)就诊时留置尿道导管,11例患者(3%)行耻骨上膀胱造瘘术,其中仅3例(0.85%)合并尿道狭窄和BPH。仅131例(26%)患者检测了PSA,范围为2 - 100 ng/ml,其中39例(29.8%,n = 131)患者PSA超过4 ng/ml且患有前列腺癌,1例患者(0.8%,n = 131)PSA水平为4 ng/ml且患有前列腺恶性肿瘤。住院时间为1 - 32天(平均7.9天),平均随访期为5.6个月(范围0 - 六十个月),并发症发生率为17.5%,包括尿路感染(UTI)7.2%、睾丸炎2.2%、尿失禁0.6%、无张力膀胱1%、勃起功能障碍0.6%、脑血管意外0.4%心肌梗死0.4%、深静脉血栓形成0.4%和弥散性血管内凝血(DIC)0.6%,死亡率为1.2%。包括入院前检查在内的治疗费用为615.00美元(范围300 - 1300美元)
尽管在卢思/良性前列腺增生的微创治疗方面取得了进展,但经尿道前列腺切除术(TURP)仍是撒哈拉以南非洲老年男性的最佳治疗选择。然而,由于卫生资源分配不佳、设施不足和培训不足,该地区大多数患者无法获得这种治疗。