Tran Hien, Kamino Hideko, Walters Ruth F
Department of Dermatology, New York University, USA.
Dermatol Online J. 2008 Oct 15;14(10):7.
A 64-year-old man presented for evaluation of tender pustules that developed on his right hand and subsequently spread up his arms in a sporotrichoid manner. Owing to the prominent history of recent trauma followed by fish tank exposure, the patient was started on doxycycline for coverage of Mycobacterium marinum. Subsequent tissue culture grew M. marinum and confirmed the clinical diagnosis. M. marinum is an atypical mycobacteria that is ubiquitously found in aquatic environments. Owing to its optimal growth temperature of 25 to 35 degrees C, infections in humans are mostly restricted to the skin. Furthermore, the organism can spread by lymphatic drainage leading to the clinical appearance of sporotrichoid lesions. The preferred treatment for M. marinum is doxycycline, which was started in our patient and has subsequently improved his clinical condition.
一名64岁男性因右手出现疼痛性脓疱前来就诊,这些脓疱随后以孢子丝菌病样方式蔓延至双臂。由于近期有明显的外伤史且接触过鱼缸,该患者开始服用强力霉素以覆盖海分枝杆菌。随后的组织培养培养出海分枝杆菌,证实了临床诊断。海分枝杆菌是一种非典型分枝杆菌,在水生环境中普遍存在。由于其最佳生长温度为25至35摄氏度,人类感染大多局限于皮肤。此外,该病原体可通过淋巴引流传播,导致孢子丝菌病样病变的临床表现。海分枝杆菌的首选治疗药物是强力霉素,我们的患者已开始服用,其临床状况随后有所改善。