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伴有和不伴有精神障碍的患者中符合指南的丙型肝炎病毒检测与报告

Guideline-concordant hepatitis C virus testing and notification among patients with and without mental disorders.

作者信息

Kilbourne Amy M, McCarthy John F, Himelhoch Seth, Welsh Deborah, Hauser Peter, Blow Frederic C

机构信息

VA Serious Mental Illness Treatment Research and Evaluation Center, Ann Arbor, MI 48105, USA.

出版信息

Gen Hosp Psychiatry. 2008 Nov-Dec;30(6):495-500. doi: 10.1016/j.genhosppsych.2008.06.002. Epub 2008 Aug 9.

Abstract

OBJECTIVE

We compared screening for hepatitis C virus (HCV), positive HCV test rates and test result notification among Veterans Affairs (VA) patients diagnosed with psychosis (e.g., schizophrenia, bipolar disorder) or depression or those with no psychiatric diagnosis.

METHOD

We identified all patients in the VA's External Peer Review Program national random sample of chart reviews regarding HCV care in fiscal year 2004. We then identified individuals diagnosed with psychosis or depression using data from the VA's National Psychosis and Depression registries. Using multivariable logistic regression and generalized estimating equation analyses, we evaluated associations between mental disorder diagnosis and receipt of HCV screening and notification of results.

RESULTS

Out of 19,397 patients, 94% received HCV tests. Of those tested, 6.9% were HCV positive, and of those who were positive, 48.2% were notified of their result within 60 days. After adjusting for demographic and clinical factors (including illicit drug use and comorbidities), individuals with psychosis or depression were no less likely to have a positive test or be notified of their result < or =60 days compared to nonpsychiatric groups. Those with drug use disorder diagnoses (OR=4.64; P<.001) and Blacks (OR=1.96; P<.001) were more likely to have a positive test.

CONCLUSIONS

Study limitations included inability to fully control for sociodemographic confounders (e.g., homelessness, incarceration). Nevertheless, we found that although the vast majority of patients were tested, only half were notified of test results. VA HCV prevention and follow-up strategies focus on enhanced notification overall and tailoring HCV risk reduction programs to minorities and those with drug use disorders.

摘要

目的

我们比较了退伍军人事务部(VA)中被诊断患有精神病(如精神分裂症、双相情感障碍)或抑郁症的患者以及无精神疾病诊断的患者在丙型肝炎病毒(HCV)筛查、HCV检测阳性率和检测结果通知方面的情况。

方法

我们在VA的外部同行评审计划2004财年关于HCV护理的全国随机图表审查样本中确定了所有患者。然后,我们使用VA的国家精神病和抑郁症登记处的数据确定了被诊断患有精神病或抑郁症的个体。通过多变量逻辑回归和广义估计方程分析,我们评估了精神障碍诊断与接受HCV筛查及结果通知之间的关联。

结果

在19397名患者中,94%接受了HCV检测。在接受检测的患者中,6.9%为HCV阳性,在这些阳性患者中,48.2%在60天内收到了检测结果通知。在调整了人口统计学和临床因素(包括非法药物使用和合并症)后,与非精神疾病组相比,患有精神病或抑郁症的个体检测呈阳性或在≤60天内收到结果通知的可能性并不更低。患有药物使用障碍诊断的患者(OR = 4.64;P <.001)和黑人(OR = 1.96;P <.001)检测呈阳性的可能性更大。

结论

研究的局限性包括无法完全控制社会人口学混杂因素(如无家可归、监禁)。尽管如此,我们发现,虽然绝大多数患者接受了检测,但只有一半的患者收到了检测结果通知。VA的HCV预防和随访策略总体上侧重于加强通知,并针对少数族裔和患有药物使用障碍的人群量身定制HCV风险降低计划。

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