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[通过铟-111 奥克辛血小板闪烁显像诊断的二尖瓣人工瓣膜血栓形成病例报告]

[A case report of a thrombosed mitral prosthesis diagnosed by 111In-oxine platelets scintigraphy].

作者信息

Otaki M, Kawashima M, Yamaguchi A, Kitamura N

机构信息

Department of Cardiovascular Surgery, National Ohsaka Hospital.

出版信息

Kokyu To Junkan. 1991 May;39(5):501-3.

PMID:1906194
Abstract

The purpose of this report was to evaluate the efficacy of 111In-oxine labeled platelets scintigraphy for detection of thrombus in the prosthetic valve. A 50-year-old man underwent re-mitral valve replacement with a Björk-Shiley prosthesis because of malfunction of the xenograft in a previous operation. Almost one year later, this patient suffered from peripheral embolism and sight disturbance. There was no evidence of a thrombosed valve although it was suspected. Cineradiography showed the valve almost fully open, and there were no abnormal sounds when the valve closed. 111In-oxine labeled platelets scintigraphy was performed for the detection of thrombus in the mitral position. Hot areas of high quality in the scintigram were demonstrated in the mitral position. As a result, Björk-Shiley prosthesis was replaced with a Duromedics prosthesis. A small thrombus (10mm) surrounded by fresh tiny thrombi was found in a minor orifice of the Björk-Shiley prosthesis.

摘要

本报告的目的是评估铟-111 奥克辛标记血小板闪烁显像术检测人工瓣膜血栓的疗效。一名 50 岁男性因先前手术中异种移植物功能障碍接受了带 Björk-Shiley 人工瓣膜的二尖瓣置换术。大约一年后,该患者出现外周栓塞和视力障碍。尽管怀疑有瓣膜血栓形成,但未发现相关证据。电影血管造影显示瓣膜几乎完全开放,瓣膜关闭时无异常声音。进行了铟-111 奥克辛标记血小板闪烁显像术以检测二尖瓣位置的血栓。闪烁显像图中二尖瓣位置显示出高质量的热点。结果,将 Björk-Shiley 人工瓣膜更换为 Duromedics 人工瓣膜。在 Björk-Shiley 人工瓣膜的一个小孔中发现了一个小血栓(10 毫米),周围有新鲜的微小血栓。

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