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腹腔镜胆囊切除术治疗小儿胆道运动障碍是安全有效的。

Laparoscopic cholecystectomy for treatment of biliary dyskinesia is safe and effective in the pediatric population.

作者信息

Hofeldt Matthew, Richmond Bryan, Huffman Kristy, Nestor Jennings, Maxwell Damian

机构信息

Department of Surgery, West Virginia University/Charleston Division, Charleston, West Virginia 25304, USA.

出版信息

Am Surg. 2008 Nov;74(11):1069-72.

Abstract

Experience with laparoscopic cholecystectomy for biliary dyskinesia in children remains limited. The aim of this study was to examine the results of a single institution's experience with laparoscopic cholecystectomy for the treatment biliary dyskinesia in the pediatric population. Medical records were reviewed on all patients younger than age 18 who underwent laparoscopic cholecystectomy at our institution from July 2004 to December 2006. Patients undergoing surgery for biliary dyskinesia, as evidenced by a preoperative gallbladder ejection fraction of 40 per cent or less, comprised the study group. Of the 51 pediatric laparoscopic cholecystectomies, 30 (58.8%) were performed for biliary dyskinesia. The patients' ages ranged from 7 to 17 (mean, 12.67 years; SD, 2.75). Symptoms consisted of chronic right upper quadrant pain (96.67%), nausea/vomiting (73.33%), back pain (30.0%), weight loss (13.33%), and a history of pancreatitis (6.66%). The amount of time between onset of symptoms and surgery was as follows: 1 to 3 months (34.62%), 4 to 6 months (30.77%), 7 to 12 months (7.69%), and greater than 1 year (26.92%). Gallbladder ejection fraction ranged from 1 to 36 per cent (mean, 14.7%). Seven of the 30 (26.67%) underwent endoscopic evaluation as part of their preoperative workup (six upper endoscopy, one colonoscopy), all of which were noncontributory. Pathology revealed chronic cholecystitis in 26 of 30 (93.3%), no abnormalities in three of 30 (10.0%), and unexpected cholelithiasis in one of 30 (3.33%). No perioperative complications were encountered. Twenty-nine of the 30 patients were available for follow up and all but one reported relief of symptoms (96.55%). This study supports the use of laparoscopic cholecystectomy as a safe and effective treatment for biliary dyskinesia in the pediatric population. The success rate in our study was substantially higher than that reported in previous series. Routine preoperative endoscopy was not used and was reserved for investigation of ambiguous or unrelated complaints.

摘要

儿童胆囊运动障碍的腹腔镜胆囊切除术经验仍然有限。本研究的目的是探讨一家机构针对小儿人群胆囊运动障碍进行腹腔镜胆囊切除术的经验结果。回顾了2004年7月至2006年12月期间在本机构接受腹腔镜胆囊切除术的所有18岁以下患者的病历。术前胆囊排空分数为40%或更低证明为胆囊运动障碍而接受手术的患者组成研究组。在51例小儿腹腔镜胆囊切除术中,30例(58.8%)是因胆囊运动障碍而进行的。患者年龄范围为7至17岁(平均12.67岁;标准差2.75)。症状包括慢性右上腹疼痛(96.67%)、恶心/呕吐(73.33%)、背痛(30.0%)、体重减轻(13.33%)和胰腺炎病史(6.66%)。症状出现至手术的时间如下:1至3个月(34.62%)、4至6个月(30.77%)、7至12个月(7.69%)和超过1年(26.92%)。胆囊排空分数范围为1%至36%(平均14.7%)。30例中有7例(26.67%)在术前检查中接受了内镜评估(6例上消化道内镜检查,1例结肠镜检查),所有这些检查均无阳性发现。病理显示30例中有26例(93.3%)为慢性胆囊炎,30例中有3例(10.0%)无异常,30例中有1例(3.33%)意外发现胆结石。未遇到围手术期并发症。30例患者中有29例可供随访,除1例外所有患者均报告症状缓解(96.55%)。本研究支持腹腔镜胆囊切除术作为小儿人群胆囊运动障碍的一种安全有效的治疗方法。我们研究中的成功率显著高于先前系列报道的成功率。未使用常规术前内镜检查,仅用于对不明确或无关主诉的调查。

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