Haricharan Ramanath N, Proklova Lyudmila V, Aprahamian Charles J, Morgan Traci L, Harmon Carroll M, Barnhart Douglas C, Saeed Shehzad A
Department of Surgery, Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
J Pediatr Surg. 2008 Jun;43(6):1060-4. doi: 10.1016/j.jpedsurg.2008.02.032.
The purpose of this study was to determine the effectiveness of laparoscopic cholecystectomy in children with biliary dyskinesia.
Reports of children with an abnormal cholecystokinin (CCK)-stimulated HIDA scan between January 2001 and July 2006 who underwent laparoscopic cholecystectomy were reviewed. Postoperatively, a 23-item Likert scale, symptom questionnaire was administered to parents.
Sixty-four children with chronic abdominal pain and no gallstones on ultrasound had an abnormal CCK-HIDA scan. Twenty-three children (median age, 14 years; 16 girls), with mean (SD) ejection fraction of 17% (8), underwent laparoscopic cholecystectomy and were further analyzed. Preoperatively, these children had right upper quadrant/epigastric pain (78%), nausea (52%), vomiting (43%), and generalized abdominal pain (22%) lasting for a median of 3 months (range, 1 month to 2.5 years). Median postoperative follow-up was 2.7 years. Sixteen (70%) parents completed the questionnaire. Of those who responded, 63% indicated that their children had no abdominal pain, 87% had no vomiting, and 69% had no nausea in the month preceding the questionnaire. Overall, 67% of parents indicated that their children's symptoms were completely relieved after cholecystectomy, whereas 7% indicated that the symptoms were not relieved.
Laparoscopic cholecystectomy is effective in providing both short-term and long-term improvement of symptoms in children with biliary dyskinesia.
本研究旨在确定腹腔镜胆囊切除术对胆囊运动障碍患儿的疗效。
回顾2001年1月至2006年7月间接受腹腔镜胆囊切除术的胆囊收缩素(CCK)刺激的肝胆动态显像异常患儿的报告。术后,向家长发放一份包含23项李克特量表的症状问卷。
64例超声检查无胆结石的慢性腹痛患儿CCK-肝胆动态显像异常。23例患儿(中位年龄14岁;16例女孩)平均(标准差)排空分数为17%(8),接受了腹腔镜胆囊切除术并进行进一步分析。术前,这些患儿有右上腹/上腹部疼痛(78%)、恶心(52%)、呕吐(43%)和全腹痛(22%),持续时间中位数为3个月(范围1个月至2.5年)。术后中位随访时间为2.7年。16名(70%)家长完成了问卷。在做出回应的家长中,63%表示他们的孩子在问卷前一个月没有腹痛,87%没有呕吐,69%没有恶心。总体而言,67%的家长表示他们孩子的症状在胆囊切除术后完全缓解,而7%表示症状未缓解。
腹腔镜胆囊切除术能有效改善胆囊运动障碍患儿的短期和长期症状。