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腹腔镜胆囊切除术治疗儿童胆囊运动障碍可持久缓解症状。

Laparoscopic cholecystectomy for biliary dyskinesia in children provides durable symptom relief.

作者信息

Haricharan Ramanath N, Proklova Lyudmila V, Aprahamian Charles J, Morgan Traci L, Harmon Carroll M, Barnhart Douglas C, Saeed Shehzad A

机构信息

Department of Surgery, Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

出版信息

J Pediatr Surg. 2008 Jun;43(6):1060-4. doi: 10.1016/j.jpedsurg.2008.02.032.

Abstract

PURPOSE

The purpose of this study was to determine the effectiveness of laparoscopic cholecystectomy in children with biliary dyskinesia.

METHODS

Reports of children with an abnormal cholecystokinin (CCK)-stimulated HIDA scan between January 2001 and July 2006 who underwent laparoscopic cholecystectomy were reviewed. Postoperatively, a 23-item Likert scale, symptom questionnaire was administered to parents.

RESULTS

Sixty-four children with chronic abdominal pain and no gallstones on ultrasound had an abnormal CCK-HIDA scan. Twenty-three children (median age, 14 years; 16 girls), with mean (SD) ejection fraction of 17% (8), underwent laparoscopic cholecystectomy and were further analyzed. Preoperatively, these children had right upper quadrant/epigastric pain (78%), nausea (52%), vomiting (43%), and generalized abdominal pain (22%) lasting for a median of 3 months (range, 1 month to 2.5 years). Median postoperative follow-up was 2.7 years. Sixteen (70%) parents completed the questionnaire. Of those who responded, 63% indicated that their children had no abdominal pain, 87% had no vomiting, and 69% had no nausea in the month preceding the questionnaire. Overall, 67% of parents indicated that their children's symptoms were completely relieved after cholecystectomy, whereas 7% indicated that the symptoms were not relieved.

CONCLUSION

Laparoscopic cholecystectomy is effective in providing both short-term and long-term improvement of symptoms in children with biliary dyskinesia.

摘要

目的

本研究旨在确定腹腔镜胆囊切除术对胆囊运动障碍患儿的疗效。

方法

回顾2001年1月至2006年7月间接受腹腔镜胆囊切除术的胆囊收缩素(CCK)刺激的肝胆动态显像异常患儿的报告。术后,向家长发放一份包含23项李克特量表的症状问卷。

结果

64例超声检查无胆结石的慢性腹痛患儿CCK-肝胆动态显像异常。23例患儿(中位年龄14岁;16例女孩)平均(标准差)排空分数为17%(8),接受了腹腔镜胆囊切除术并进行进一步分析。术前,这些患儿有右上腹/上腹部疼痛(78%)、恶心(52%)、呕吐(43%)和全腹痛(22%),持续时间中位数为3个月(范围1个月至2.5年)。术后中位随访时间为2.7年。16名(70%)家长完成了问卷。在做出回应的家长中,63%表示他们的孩子在问卷前一个月没有腹痛,87%没有呕吐,69%没有恶心。总体而言,67%的家长表示他们孩子的症状在胆囊切除术后完全缓解,而7%表示症状未缓解。

结论

腹腔镜胆囊切除术能有效改善胆囊运动障碍患儿的短期和长期症状。

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