人类李斯特菌病的流行病学
Epidemiology of human listeriosis.
作者信息
Schuchat A, Swaminathan B, Broome C V
机构信息
Meningitis and Special Pathogens Branch, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
出版信息
Clin Microbiol Rev. 1991 Apr;4(2):169-83. doi: 10.1128/CMR.4.2.169.
Abstract
During the 1980s, investigation of several large epidemics of listeriosis confirmed that transmission of L. monocytogenes in food causes human disease. Progress in laboratory detection and subtyping of the organism has enhanced our ability to compare human and environmental isolates of L. monocytogenes. Transmission by foodborne organisms is now recognized as causing both epidemic and sporadic listeriosis. Continued study of dietary risk factors associated with listeriosis is needed in order to develop dietary recommendations for the expanding population at increased risk of disease. Current research application of new molecular methods to the study of L. monocytogenes may improve the ability to diagnose pregnancy-associated disease and permit the rapid detection and control of L. monocytogenes in the food supply.
摘要
在20世纪80年代，对几起大规模李斯特菌病疫情的调查证实，单核细胞增生李斯特菌在食物中的传播会引发人类疾病。该生物体在实验室检测和分型方面的进展提高了我们比较人类和环境中单核细胞增生李斯特菌分离株的能力。食源性病原体的传播现已被确认为会导致流行性和散发性李斯特菌病。为了针对疾病风险增加的不断扩大的人群制定饮食建议，需要继续研究与李斯特菌病相关的饮食风险因素。目前将新分子方法应用于单核细胞增生李斯特菌研究的成果可能会提高诊断妊娠相关疾病的能力，并能在食品供应中快速检测和控制单核细胞增生李斯特菌。
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