Khermosh O, Wientroub S
Tel Aviv Medical Center, Israel.
J Bone Joint Surg Br. 1991 Jul;73(4):621-5. doi: 10.1302/0301-620X.73B4.1906473.
We made a prospective longitudinal clinical and radiological study of 18 children diagnosed as having dysplasia epiphysealis capitis femoris. Half the cases were bilateral. Boys were affected five times more often than girls. There were no symptoms or clinical signs in most but some of the bilateral cases had an inconsistent waddling gait. The imaging studies suggest that the cartilaginous proximal femoral epiphysis is hypoplastic, with delayed appearance of single or multiple ossification centres. Progressive improvement occurred and at an average age of five years and six months, there was complete fusion of all the ossific nuclei and normal density and texture of the epiphyseal bone. The end result was a round epiphysis with a slightly diminished height. The dysplasia is attributed to focal hypoplasia of the proximal femoral epiphysis.
我们对18名被诊断为股骨头骨骺发育异常的儿童进行了前瞻性纵向临床和影像学研究。半数病例为双侧受累。男孩的发病率是女孩的五倍。大多数患儿没有症状或临床体征，但一些双侧病例有不一致的蹒跚步态。影像学研究表明，股骨近端软骨骨骺发育不全，单个或多个骨化中心出现延迟。病情逐渐改善，平均在五岁零六个月时，所有骨化核完全融合，骨骺骨密度和质地正常。最终结果是骨骺呈圆形，高度略有降低。这种发育异常归因于股骨近端骨骺的局灶性发育不全。
