Obana Y, Nishino T
Department of Microbiology, Kyoto Pharmaceutical University.
Kansenshogaku Zasshi. 1991 Apr;65(4):442-6. doi: 10.11150/kansenshogakuzasshi1970.65.442.
The infectivity of Enterococcus faecalis was compared with that of Escherichia coli in the urinary tract in mice. The infectivity of E. faecalis in normal mice was found to be equal to that of E. coli. The mice previously treated with cyclophosphamide, carrageenin or alloxan as the immunosuppressive drug, and restricted water supply, were more susceptible to enterococcal infection than non-treated ones. These data were confirmed with histological examinations. E. faecalis is a pathogenic organism in the urinary tract and therefore cautions should be given to the treatment in clinical practice.
在小鼠尿路中比较了粪肠球菌和大肠杆菌的感染性。发现粪肠球菌在正常小鼠中的感染性与大肠杆菌相当。先前用环磷酰胺、角叉菜胶或四氧嘧啶作为免疫抑制药物处理并限制供水的小鼠,比未处理的小鼠更容易受到肠球菌感染。这些数据通过组织学检查得到证实。粪肠球菌是尿路中的致病生物,因此在临床实践中应谨慎对待其治疗。