Finnbogadóttir Anna Freyja, Petersen Hannes, Laxdal Thröstur, Gudbrandsson Fridrik, Gudnason Thörolfur, Haraldsson Asgeir
Faculty of Medicine, University of Iceland.
Scand J Infect Dis. 2009;41(2):95-8. doi: 10.1080/00365540802593461.
The incidence of mastoiditis, a known complication of otitis media, may reflect the incidence and treatment of otitis media. The aim of the study was to evaluate the incidence of mastoiditis in Iceland, especially in children, and the possible correlation with antibiotic usage. Patients with mastoiditis during 1984-2002 were identified and information on antibiotic usage in children in the y 1989-2002 was obtained. 84 patients were diagnosed with mastoiditis during 1984-2002, 52 (62%) of whom were less than 18 y of age. 26 (50%) children were less than 3 y of age. During the y 1999-2002, 28 children were diagnosed with mastoiditis, of whom 15 (54%) were diagnosed with otitis media within a week prior to admission. 11 (73%) were treated with antibiotics and 4 (27%) were not. During 1989-2002 a correlation was detected between decreased antibiotic usage in children and increased incidence of mastoiditis (r=-0.68; p=0.007). Following changes in guidelines for antibiotic prescriptions for otitis media in Iceland during the 1990s, antibiotic usage decreased but the incidence of mastoiditis increased. It is uncertain if this is a causal relationship. It is important to treat otitis media correctly while being alert for complications, especially in young children.
乳突炎是中耳炎的一种已知并发症,其发病率可能反映中耳炎的发病率和治疗情况。本研究的目的是评估冰岛乳突炎的发病率,尤其是儿童中的发病率,以及与抗生素使用的可能相关性。确定了1984年至2002年期间患有乳突炎的患者,并获取了1989年至2002年期间儿童抗生素使用情况的信息。1984年至2002年期间,84例患者被诊断为乳突炎,其中52例(62%)年龄小于18岁。26例(50%)儿童年龄小于3岁。在1999年至2002年期间,28例儿童被诊断为乳突炎,其中15例(54%)在入院前一周内被诊断为中耳炎。11例(73%)接受了抗生素治疗,4例(27%)未接受治疗。1989年至2002年期间,发现儿童抗生素使用减少与乳突炎发病率增加之间存在相关性(r=-0.68;p=0.007)。20世纪90年代冰岛中耳炎抗生素处方指南发生变化后,抗生素使用减少,但乳突炎发病率增加。这是否为因果关系尚不确定。正确治疗中耳炎同时警惕并发症很重要,尤其是在幼儿中。