Pouw R E, Sharma V K, Bergman J J, Fleischer D E
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
Endoscopy. 2008 Dec;40(12):1033-40. doi: 10.1055/s-0028-1103421. Epub 2008 Dec 8.
Stepwise circumferential and focal radiofrequency ablation using the HALO system is a novel and promising ablative modality for Barrett's esophagus. Primary circumferential ablation is performed using a balloon-based bipolar electrode, while secondary treatment of residual Barrett's epithelium is performed using an endoscope-mounted bipolar electrode on an articulated platform. It has been used as a single-modality treatment or in combination with other therapies. Recent studies suggest that this ablation technique is highly effective in removing Barrett's mucosa and its associated dysplasia without the known drawbacks of photodynamic therapy or argon plasma coagulation, such as esophageal stenosis and subsquamous foci of intestinal metaplasia (also known as "buried Barrett"). [nl]In this review paper we will explain the technical background of radiofrequency ablation using the HALO system, give a summary of its current status, and speculate on possible future applications.
使用HALO系统进行逐步圆周和局部射频消融是一种针对巴雷特食管的新颖且有前景的消融方式。初次圆周消融使用基于球囊的双极电极进行，而对残留巴雷特上皮的二次治疗则使用关节平台上的内镜安装双极电极进行。它已被用作单一治疗方式或与其他疗法联合使用。近期研究表明，这种消融技术在去除巴雷特黏膜及其相关异型增生方面非常有效，且没有光动力疗法或氩等离子体凝固术的已知缺点，如食管狭窄和肠化生的黏膜下病灶（也称为“隐匿性巴雷特”）。[荷兰语]在这篇综述论文中，我们将解释使用HALO系统进行射频消融的技术背景，并总结其现状，同时推测其未来可能的应用。
