Yen Cheng-Fang, Chen Cheng-Chung, Cheng Chung-Ping, Yen Chia-Nan, Lin Huang-Chi, Ko Chih-Hung, Yen Ju-Yu, Chen Cheng-Sheng
Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Psychiatry Clin Neurosci. 2008 Dec;62(6):685-90. doi: 10.1111/j.1440-1819.2008.01870.x.
To compare the level of insight among six groups of patients with psychiatric disorders, including those with schizophrenia (SZ), bipolar I disorder (BP), or depressive disorders (DD) who had or did not have comorbid alcohol use disorder (AUD).
A total of 285 outpatients meeting the aforementioned criteria were recruited into the study. The Schedule of Assessment of Insight-Expanded version (SAI-E) was used to measure subjects' insight. Analysis of covariance (ancova) was used to compare the levels of insight among the six groups of subjects.
Regardless of whether patients had comorbid AUD or not, patients with DD had higher levels of insight than did patients with SZ. Comorbid AUD had independent effects on the differences in the level of insight between patients with DD and BP and between patients with BP and SZ. No statistically significant difference in insight was found between patients with the same psychiatric diagnosis with and without comorbid AUD.
In addition to psychotic features and clinical states, comorbid AUD should be taken into consideration when comparing the level of insight among patients with different psychiatric diagnoses.
比较六组精神障碍患者的自知力水平，这六组患者包括患有或未患有合并酒精使用障碍（AUD）的精神分裂症（SZ）、双相I型障碍（BP）或抑郁症（DD）患者。
总共 285 名符合上述标准的门诊患者被纳入研究。采用自知力评估量表扩展版（SAI-E）来测量受试者的自知力。使用协方差分析（ancova）比较六组受试者的自知力水平。
无论患者是否合并 AUD，DD 患者的自知力水平均高于 SZ 患者。合并 AUD 对 DD 患者与 BP 患者之间以及 BP 患者与 SZ 患者之间自知力水平的差异具有独立影响。在患有相同精神疾病诊断且合并或未合并 AUD 的患者之间，自知力未发现统计学上的显著差异。
在比较不同精神疾病诊断患者的自知力水平时，除了精神病性特征和临床状态外，还应考虑合并 AUD 的情况。
