Singh Inder M, Shishehbor Mehdi H, Christofferson Ryan D, Tuzcu E Murat, Kapadia Samir R
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, OH 44195, USA.
Cleve Clin J Med. 2008 Nov;75(11):805-12. doi: 10.3949/ccjm.75.11.805.
Aortic valve replacement via open heart surgery, although still the standard treatment for severe symptomatic aortic valve stenosis, is not an option for many patients with severe symptoms, and these patients are often left with suboptimal strategies such as medical management or balloon valvuloplasty. But over the last 5 years improvements in percutaneous approaches to implantation of prosthetic aortic valves have made it a potential therapeutic option for these patients. Technical and device issues are being refined, and percutaneous aortic valve replacement is showing promise in ongoing clinical trials.
通过心脏直视手术进行主动脉瓣置换,尽管仍是严重有症状主动脉瓣狭窄的标准治疗方法,但对于许多有严重症状的患者来说并非一种选择,这些患者往往只能采用诸如药物治疗或球囊瓣膜成形术等不太理想的策略。但在过去5年里,人工主动脉瓣经皮植入方法的改进使其成为这些患者的一种潜在治疗选择。技术和器械问题正在不断完善,经皮主动脉瓣置换术在正在进行的临床试验中显示出前景。