Milonas Daimantas, Saferis Viktoras, Jievaltas Mindaugas
Department of Urology, Kaunas University of Medicine, Kaunas, Lithuania.
Urol Int. 2008;81(4):421-6. doi: 10.1159/000167840. Epub 2008 Dec 10.
The objective of this study was to establish the influence of preoperative parameters on unfavorable outcomes after transurethral resection of the prostate.
In a prospective study, 90 patients underwent transurethral resection of the prostate. The standardized protocol was used to investigate parameters, preoperatively and after 6 months. The baseline values were analyzed with respect to the probability of predicting the effectiveness of the outcome.
All preoperative parameters changed significantly, from 55.1 to 116% (p < 0.001). Treatment was effective for 85.6% of the patients, and the outcomes were unfavorable for 14.4%. The monovariate analysis detected the transition zone index (cut-off 0.48, p = 0.002, OR 7.48) as independent predictor of ineffective outcome. Logistic regression analysis found two the most important parameters - transition zone index (OR 30.26, p = 0.002) and bothersomeness of voiding symptoms (OR 20.7, p = 0.008) for unfavorable outcomes.
The parameters that are traditionally used cannot predict unfavorable outcomes. The transition zone index and bothersomeness of voiding symptoms are most important parameters for predicting an unfavorable outcome after TURP.
本研究的目的是确定术前参数对经尿道前列腺电切术后不良结局的影响。
在一项前瞻性研究中，90例患者接受了经尿道前列腺电切术。采用标准化方案对术前及术后6个月的参数进行研究。对基线值进行分析，以预测结局有效性的概率。
所有术前参数均有显著变化，从55.1%至116%（p < 0.001）。85.6%的患者治疗有效，14.4%的患者结局不佳。单变量分析发现移行区指数（临界值0.48，p = 0.002，OR 7.48）是无效结局的独立预测因素。逻辑回归分析发现两个最重要的参数——移行区指数（OR 30.26，p = 0.002）和排尿症状困扰程度（OR 20.7，p = 0.008）与不良结局相关。
传统使用的参数无法预测不良结局。移行区指数和排尿症状困扰程度是预测经尿道前列腺电切术后不良结局的最重要参数。
