Kim Yong Tae
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2008 Oct;52(4):214-9.
Intraductal papillary mucinous neoplasm (IPMN) is frequently found recently and is a precancerous lesion. Main duct-type should be resected since it can easily progress to invasive IPMN, whereas branch duct-type (BD) usually remains silent without malignant transformation. BD-IPMN should be resected if it has mural nodule, thick wall or septum, or solid component which are the obvious risk factors for malignancy. If the cyst size of BD-IPMN is more than 3 cm in diameter without obvious risk factors, it can be followed-up regularly or can be treated either with surgical resection or endoscopic ultrasonography (EUS)-guided ethanol lavage. Small BD-IPMN less than 3 cm in size without risk factors can be followed up with sonography, CT scan or EUS annually.
导管内乳头状黏液性肿瘤(IPMN)近年来屡有发现,是一种癌前病变。主胰管型应行切除,因为其容易进展为浸润性IPMN,而分支胰管型(BD)通常无恶变而保持静止状态。BD-IPMN若有壁结节、厚壁或分隔,或有实性成分,这些均为明显的恶变危险因素,则应行切除。若BD-IPMN囊肿直径大于3 cm且无明显危险因素,可定期随访,或行手术切除或内镜超声(EUS)引导下乙醇灌洗治疗。直径小于3 cm且无危险因素的小BD-IPMN可每年通过超声、CT扫描或EUS进行随访。