[CT引导下放射性粒子（125）I植入治疗多发骨转移]
[CT guided radioactive seed (125)I implantation in treating multiple bone metastasis].
作者信息
Zhang Jiu-quan, Huang Xue-quan, Zhang Jing, Cai Ping, Chen Wei, Wang Jian, Zhou Dai-quan, Zhang En-quan
机构信息
Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
出版信息
Zhonghua Yi Xue Za Zhi. 2008 Oct 28;88(39):2739-42.
OBJECTIVE
To investigate the clinical value of CT guided radioactive seed (125)I implantation in treating bone metastasis.
METHODS
28 multiple bone metastatic tumor patients with 116 metastatic lesions totally, adenocarcinoma of lung in 6 cases, squamous cell carcinoma of lung, renal clear-cell carcinoma, and carcinoma of prostate in 4 cases each, hepatocellular carcinoma and colon carcinoma in 3 cases each, breast carcinoma in 2 cases, and malignant schwannoma and pancreatic cancer in 1 case each, 13 males and 15 females, aged 49.8, underwent CT guided radioactive seed (125)I implantation into bone metastatic lesions.
RESULTS
In these 28 cases, complete pain relief (CR) was observed in 16 cases, partial relief (PR) in 7 cases, and no change (NC) in 5 cases with an effective rate of 82.1%. Among the 116 lesions in these 28 cases local control (LC) was seen in 93 cases, NC in 17, and PD in 6. The response rate was 80.2%.
CONCLUSION
CT guided radioactive seed (125)I implantation procedure has good clinical effects in treating bone metastasis with minimal invasive and few complications.
目的
探讨CT引导下放射性粒子（125）I植入治疗骨转移瘤的临床价值。
方法
28例多发骨转移瘤患者，共116个转移病灶，其中肺癌腺癌6例，肺鳞癌、肾透明细胞癌、前列腺癌各4例，肝癌、结肠癌各3例，乳腺癌2例，恶性神经鞘瘤、胰腺癌各1例；男13例，女15例，年龄49.8岁，均接受CT引导下放射性粒子（125）I植入骨转移瘤病灶。
结果
28例患者中，16例疼痛完全缓解（CR），7例部分缓解（PR），5例无变化（NC），有效率82.1%。28例患者的116个病灶中，93个病灶局部控制（LC），17个病灶NC，6个病灶进展（PD），有效率80.2%。
结论
CT引导下放射性粒子（碘-125）植入术治疗骨转移瘤临床效果良好，具有微创、并发症少的优点。
Zotero 插件