Mera Menéndez Fernando, Alvarez Carrillo Solssiree, Hinojar Gutiérrez Adolfo, Nieto Santiago, Raboso García-Baquero Eduardo
Servicio de Otorrinolaringología, Hospital Universitario de La Princesa, Madrid, España.
Acta Otorrinolaringol Esp. 2008 Nov;59(9):469-71.
We present a 73-year-old woman with progressive dysphagia and dysarthria over two years associated with systemic symptoms including weight loss, asthenia and dyspnoea. Biopsy of the tongue demonstrated amyloid AL deposits. The immunohistochemical study showed a notable positiveness to antibodies for L-kappa chains. The patient died 6 months after diagnosis.
我们报告一位73岁女性，两年来出现进行性吞咽困难和构音障碍，并伴有体重减轻、乏力和呼吸困难等全身症状。舌活检显示有淀粉样轻链（AL）沉积。免疫组化研究显示对L-κ链抗体有显著阳性反应。该患者在诊断后6个月死亡。
