Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Int J Cardiol. 2010 Apr 15;140(2):226-35. doi: 10.1016/j.ijcard.2008.11.033. Epub 2008 Dec 10.
Control of hypercholesterolemia is an important clinical and public health objective, yet it is generally poor. The objective of this study was to examine trends in the prevalence of hypercholesterolemia, having a cholesterol check, awareness, treatment, and control among United States adults.
We examined data for 18053 participants aged > or =20 years of the National Health and Nutrition Examination Surveys from 1999 to 2006.
The unadjusted prevalence of hypercholesterolemia ranged from 53.2% to 56.1% and changed little over the study period. Significant increases were evident in the percentage of United States adults who had their concentration of cholesterol checked (from 68.6% to 74.8%), who reported being told that they had high hypercholesterolemia (from 42.0% to 50.4%), who reported using cholesterol-lowering medications (from 39.1% to 54.4%), and who had their hypercholesterolemia controlled (from 47.0 to 64.3%). Among all participants with hypercholesterolemia control of hypercholesterolemia increased from 7.2% to 17.1%. Disparities related to gender and race or ethnicity existed, notably a lower rate of control among women than men and lower rates of having a cholesterol check and reporting being told about hypercholesterolemia among African Americans and Mexican Americans than whites.
Encouraging increases in awareness, treatment, and control of hypercholesterolemia occurred from 1999 through 2006. Nevertheless, control of hypercholesterolemia remains poor.
控制高胆固醇血症是一个重要的临床和公共卫生目标,但总体控制情况较差。本研究的目的是调查美国成年人高胆固醇血症的患病率、胆固醇检查、知晓率、治疗率和控制率的变化趋势。
我们对 1999 年至 2006 年参加国家健康和营养调查的 18053 名年龄≥20 岁的成年人的数据进行了研究。
未经调整的高胆固醇血症患病率在 53.2%至 56.1%之间,研究期间变化不大。美国成年人中有更多的人进行了胆固醇检查(从 68.6%增加到 74.8%)、报告曾被告知患有高胆固醇血症(从 42.0%增加到 50.4%)、使用降脂药物(从 39.1%增加到 54.4%),以及胆固醇血症得到控制(从 47.0%增加到 64.3%)。在所有高胆固醇血症患者中,高胆固醇血症的控制率从 7.2%增加到 17.1%。存在与性别和种族或民族有关的差异,特别是女性的控制率低于男性,非裔美国人和墨西哥裔美国人进行胆固醇检查和报告患有高胆固醇血症的比例低于白人。
1999 年至 2006 年期间,高胆固醇血症的知晓率、治疗率和控制率均有所上升。然而,高胆固醇血症的控制情况仍然较差。