Pillen Sigrid, Tak Ramon O, Zwarts Machiel J, Lammens Martin M Y, Verrijp Kiek N, Arts Ilse M P, van der Laak Jeroen A, Hoogerbrugge Peter M, van Engelen Baziel G M, Verrips Aad
Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Ultrasound Med Biol. 2009 Mar;35(3):443-6. doi: 10.1016/j.ultrasmedbio.2008.09.016. Epub 2008 Dec 10.
In this study, we examined the correlation between muscle ultrasound and muscle structure. Echo intensity (EI) of 14 muscles of two golden retriever muscular dystrophy dogs was correlated to the percentage interstitial fibrous tissue and fat in muscle biopsy. A significant correlation between interstitial fibrous tissue and EI was found (r = 0.87; p < 0.001). The separate influence of interstitial fat on muscle EI could not be established as only little fat was present. We conclude that fibrous tissue causes increased muscle EI. The high correlation between interstitial fibrous tissue and EI makes ultrasound a reliable method to determine severity of structural muscle changes.
在本研究中,我们检测了肌肉超声与肌肉结构之间的相关性。对两只患有金毛寻回犬型肌营养不良症的犬只的14块肌肉的回声强度(EI)与肌肉活检中的间质纤维组织和脂肪百分比进行了相关性分析。发现间质纤维组织与EI之间存在显著相关性(r = 0.87;p < 0.001)。由于仅存在少量脂肪,因此无法确定间质脂肪对肌肉EI的单独影响。我们得出结论,纤维组织会导致肌肉EI升高。间质纤维组织与EI之间的高度相关性使得超声成为确定肌肉结构变化严重程度的可靠方法。