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一例不明原因发热病例:(18)F-FDG-PET/CT在大动脉炎中的表现

A case of fever of unknown origin: (18)F-FDG-PET/CT findings in Takayasu's arteritis.

作者信息

Skoura Evangelia, Giannopoulou Chariklia, Keramida Georgia, Skilakaki Maria, Datseris Ioannis

机构信息

Nuclear Medicine Department, Evangelismos Hospital, 45-47, Ipsilandou street, Athens 10676, Greece.

出版信息

Hell J Nucl Med. 2008 Sep-Dec;11(3):172-4.

PMID:19081862
Abstract

This is a case of a 54 years old woman with fever of unknown origin. Physical examination showed nothing remarkable. Chest radiographs, abdominal ultrasound examination (US) and chest-abdominal-pelvic CT, showed segmental thickening of the wall of the aorta. On admission, the C-reactive protein level and the erythrocyte sedimentation rate were elevated. (18)Fluoro-fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET/CT) showed increased uptake of the aorta wall and its main branches that could be indicative of arteritis. The temporal artery biopsy was negative for giant-cell arteritis. The patient responded well to prednisolone treatment. A second (18)F-FDG-PET/CT scan showed great improvement. (18)F-FDG-PET/CT scan early indicates arteritis of the great vessels that in this case was considered to be TA and contributes in monitoring disease activity.

摘要

这是一例54岁不明原因发热的女性病例。体格检查未发现明显异常。胸部X线片、腹部超声检查(US)及胸腹部盆腔CT显示主动脉壁节段性增厚。入院时,C反应蛋白水平和红细胞沉降率升高。(18)氟脱氧葡萄糖正电子发射断层扫描((18)F-FDG-PET/CT)显示主动脉壁及其主要分支摄取增加,提示可能存在动脉炎。颞动脉活检巨细胞动脉炎结果为阴性。患者对泼尼松龙治疗反应良好。第二次(18)F-FDG-PET/CT扫描显示有显著改善。(18)F-FDG-PET/CT扫描可早期提示大血管动脉炎,在本病例中考虑为颞动脉炎,并有助于监测疾病活动。

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JMA J. 2021 Oct 15;4(4):358-366. doi: 10.31662/jmaj.2020-0115. Epub 2021 Sep 13.
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Diagnostic value of PET/CT for giant cell arteritis combined with pulmonary embolism presenting: Case report and literature review.PET/CT对巨细胞动脉炎合并肺栓塞的诊断价值:病例报告及文献复习
Medicine (Baltimore). 2017 Aug;96(31):e7651. doi: 10.1097/MD.0000000000007651.
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Bronchiectasis and hoarseness of voice in takayasu arteritis: a rare presentation.
大动脉炎中的支气管扩张和声音嘶哑:一种罕见的表现。
BMC Res Notes. 2012 Aug 20;5:447. doi: 10.1186/1756-0500-5-447.