结核分枝杆菌甲硫氨酸亚砜还原酶A的天然碳水化合物底物。
A natural carbohydrate substrate for Mycobacterium tuberculosis methionine sulfoxide reductase A.
作者信息
Stalford Susanne A, Fascione Martin A, Sasindran Smitha J, Chatterjee Delphi, Dhandayuthapani Subramanian, Turnbull W Bruce
机构信息
Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UKLS2 9JT.
出版信息
Chem Commun (Camb). 2009 Jan 7(1):110-2. doi: 10.1039/b817483k. Epub 2008 Nov 11.
DOI:10.1039/b817483k
PMID:19082015
Abstract
Enzymatic reduction of the methylsulfinylxylofuranosyl (MSX) groups in lipoarabinomannan provides proof of the absolute configuration of MSX and a possible biochemical mechanism for oxidative protection in Mycobacterium tuberculosis.
摘要
脂阿拉伯甘露聚糖中甲基亚磺酰木呋喃糖基（MSX）基团的酶促还原为MSX的绝对构型提供了证据，并为结核分枝杆菌的氧化保护提供了一种可能的生化机制。
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