用于快速先导物和靶点鉴定的反向化学遗传学
Reciprocal chemical genetics for swift lead and target identification.
作者信息
Kuijl Coenraad, Tuin Adriaan W, Overkleeft Hermen, Neefjes Jacques
机构信息
Division of Tumor Biology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands.
出版信息
Mol Biosyst. 2008 Oct;4(10):1001-8. doi: 10.1039/b803265n. Epub 2008 Jul 24.
DOI:10.1039/b803265n
PMID:19082139
Abstract
Reciprocal chemical genetics: correlation between chemical profile of in vivo phenotypes and in vitro data of potential target genes leads to swift target identification.
摘要
反向化学遗传学
体内表型的化学特征与潜在靶基因的体外数据之间的相关性可快速鉴定靶点。
Zotero 插件