Wente M N, Schmied B M, Schmidt J, Büchler M W
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
Chirurg. 2009 Jan;80(1):7-13. doi: 10.1007/s00104-008-1579-6.
Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are of increasing interest in the field of pancreatic surgery ever since their first description as an individual pancreatic tumor entity in 1982. The decision for surgical or conservative management is based on the adenoma-carcinoma sequence and the differentiation into main-duct or branch-duct IPMN. Invasive IPMN forms (carcinoma in situ and invasive carcinoma) and in particular noninvasive IPMNs (adenoma and borderline tumors) reveal significantly better survival rates than ductal adenocarcinoma of the pancreas.
自1982年胰腺导管内乳头状黏液性肿瘤（IPMN）首次被描述为一种独立的胰腺肿瘤实体以来，它在胰腺外科领域越来越受到关注。手术或保守治疗的决策基于腺瘤-癌序列以及主胰管或分支胰管IPMN的区分。侵袭性IPMN类型（原位癌和浸润性癌），尤其是非侵袭性IPMN（腺瘤和交界性肿瘤）的生存率明显高于胰腺导管腺癌。
