女性基底节区生殖细胞瘤：病例报告及文献复习
Germinoma of basal ganglia in female: case report and review of the literature.
作者信息
Hao Shuyu, Liu Baiyun, Tang Jie, Jia Ge, Zhang Yuqi, Ma Zhenyu, Wang Zhongcheng
机构信息
Beijing Neurosurgical Institute, Capital Medical University, Beijing, People's Republic of China.
出版信息
Childs Nerv Syst. 2009 May;25(5):613-7. doi: 10.1007/s00381-008-0769-3. Epub 2008 Dec 11.
INTRODUCTION
Germinoma of basal ganglia in female is very rare. The authors present a case of germinoma located in the right temporal lobe and basal ganglia in female and raise a hypothesis for the sex disparity.
MATERIALS AND METHODS
A 13-year-old Chinese girl complained of weakness in the left extremities and intermittent headache for 2 years. Neuroimaging revealed an irregular lesion in the temple lobe and basal ganglia. A temporal polectomy was performed for the tumor.
RESULTS AND DISCUSSION
Histopathologic examination confirmed germinoma. The patient remains stable and tumor-free for 36 months after radiotherapy and chemotherapy. The authors' hypothesis is that it is the individual hormone balance which leads to the male predominance of germinoma in the basal ganglia.
引言
女性基底节生殖细胞瘤非常罕见。作者报告一例位于女性右侧颞叶和基底节的生殖细胞瘤病例，并提出关于性别差异的假说。
材料与方法
一名13岁中国女孩主诉左肢无力和间歇性头痛2年。神经影像学检查显示颞叶和基底节有一不规则病灶。对该肿瘤实施了颞叶切除术。
结果与讨论
组织病理学检查确诊为生殖细胞瘤。放疗和化疗后，患者病情稳定，36个月无瘤生存。作者的假说是，个体激素平衡导致基底节生殖细胞瘤男性居多。
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