Maccioni Francesca
Department of Radiological Sciences, University of Rome Sapienza, Policlinico Umberto I, Viale Regina Elena 324, 00161, Rome, Italy.
Abdom Imaging. 2010 Feb;35(1):31-40. doi: 10.1007/s00261-008-9482-7. Epub 2008 Dec 10.
Double-contrast magnetic resonance imaging (DC-MRI) is a technique for imaging the intestine, which has shown to be very effective in assessing inflammatory bowel disease (IBD), and particularly Crohn's disease (CD). The expression derives from the association of two different contrast agents, a superparmagnetic intestinal and a paramagnetic intravenous contrast agent. This specific contrast media combination provides optimization of the tissue contrast, both on T1- and T2-weighted images, thus allowing an effective display of small and large bowel loops in normal and pathologic conditions. Therefore, main CD complications (strictures, fistulas, and abscesses), as well as disease activity, may be valuably assessed. The term DC-MRI may also be referred to the typical "double contrast" effect that is produced by this technique at the level of the inflamed bowel wall, both on T1- and T2-weighted images, directly related to the degree of wall inflammation (disease activity).
双对比磁共振成像（DC-MRI）是一种用于肠道成像的技术，已证明在评估炎症性肠病（IBD），尤其是克罗恩病（CD）方面非常有效。该技术通过联合使用两种不同的造影剂，即超顺磁性肠道造影剂和顺磁性静脉造影剂。这种特定的造影剂组合可优化T1加权和T2加权图像上的组织对比度，从而能够有效显示正常和病理状态下的大小肠肠袢。因此，可以对主要的CD并发症（狭窄、瘘管和脓肿）以及疾病活动度进行有价值的评估。术语DC-MRI也可指代该技术在T1加权和T2加权图像上，在炎症肠壁水平产生的典型“双对比”效应，这与肠壁炎症程度（疾病活动度）直接相关。
