Bilici Ahmet, Karci Ebru, Altun Eda, Ozkara Sevgiye Kacar, Uygun Kazim, Aksu Gorkem, Ustaalioglu Bala Basak Oven
Department of Medical Oncology, Dr. Lütfi Kirdar Kartal Education and Training Hospital, Istanbul, Turkey.
Arch Gynecol Obstet. 2009 Jul;280(1):153-6. doi: 10.1007/s00404-008-0868-0. Epub 2008 Dec 12.
Endometrial cancer (EC) is the most common malignancy of the female genital tract. Lymph node involvement is one of the major prognostic factors. Therefore, pelvic and paraaortic lymph nodes dissection is a part of the surgical management of these patients. Isolated peripheral lymph node metastasis has not been previously reported as a finding of recurrence in EC. We report a 67-year-old woman with recurrent EC presented with an isolated cervical lymph node metastasis (ICLM). Following the combination chemotherapy of doxorubicin, cisplatin and cyclophosphamide, her cervical lymph node was completely regressed. To our knowledge, this is the first case of recurrent EC presented with ICLM. We suggest that for women with EC who had isolated peripheral lymphadenopathies, peripheral lymph node metastasis should be considered as the finding of recurrence in patient with EC.
子宫内膜癌（EC）是女性生殖道最常见的恶性肿瘤。淋巴结受累是主要的预后因素之一。因此，盆腔和腹主动脉旁淋巴结清扫是这些患者手术治疗的一部分。孤立性外周淋巴结转移此前尚未见作为子宫内膜癌复发表现的报道。我们报告一名67岁复发性子宫内膜癌女性患者，其表现为孤立性宫颈淋巴结转移（ICLM）。在接受阿霉素、顺铂和环磷酰胺联合化疗后，其宫颈淋巴结完全消退。据我们所知，这是首例以孤立性宫颈淋巴结转移表现的复发性子宫内膜癌病例。我们建议，对于患有孤立性外周淋巴结病变的子宫内膜癌女性患者，外周淋巴结转移应被视为子宫内膜癌患者复发的表现。
