Gutierrez-Correa J, Hod M, Passoneau J V, Freinkel N
Centro de Investigación de Bioquimica y Nutrición, UNMSM, Lima, Peru.
Biol Neonate. 1991;59(5):294-302. doi: 10.1159/000243363.
Glycogen content and the enzymes of glycogen metabolism have been measured in the postimplantation rat embryo over a period ranging from 9.5 to 18.5 days of gestation. The earliest periods studied were at days 9.5 and 10.5 of gestation, when the yolk sac becomes vascularized and heart beat is first established. The next intervals were at days 10.5-11.5 when vascular connections via the allantoic placenta are formed. At 14.5 and 18.5 days of development, 4 entire organs were analyzed; heart, liver, kidney and brain. The metabolic apparatus of glycogen metabolism was concentrated in the embryo at 10.5 days, then the heart region, and in the heart itself at later stages.
在妊娠9.5至18.5天的时间段内，对植入后大鼠胚胎中的糖原含量及糖原代谢酶进行了测定。研究的最早阶段是在妊娠9.5天和10.5天，此时卵黄囊开始血管化，心脏开始跳动。接下来的时间段是在10.5 - 11.5天，此时通过尿囊胎盘形成了血管连接。在发育的14.5天和18.5天，对4个完整器官进行了分析，即心脏、肝脏、肾脏和大脑。糖原代谢的代谢机制在10.5天时集中在胚胎中，然后在心脏区域，后期则集中在心脏本身。
