Bright Janice M, Martin Julie M, Mama Khursheed
The Department of Clinical Sciences, Colorado State University, 300 W. Drake Road, Fort Collins, CO 80523-1620, USA.
J Vet Cardiol. 2005 Nov;7(2):85-96. doi: 10.1016/j.jvc.2005.07.003. Epub 2005 Oct 14.
To evaluate safety, efficacy, and clinical usefulness of biphasic transthoracic cardioversion for management of dogs with atrial fibrillation (AF).
In dogs AF is usually managed with heart rate control rather than by restoration of sinus rhythm (SR). However, restoration of SR has potential advantages of improving cardiac output and reducing ventricular filling pressures, and biphasic cardioversion provides an improved benefit/risk ratio compared to traditional monophasic cardioversion.
ANIMALS, MATERIALS AND METHODS: Retrospective analysis of data from 39 dogs with spontaneous AF managed with biphasic transthoracic cardioversion was done. Conversion characteristics, adverse effects, and duration of SR were evaluated. Effects of heart disease and pretreatment with amiodarone on success of cardioversion and on duration of SR were also evaluated.
Restoration of SR was achieved in 36 of 39 dogs (92.3%). Presence of heart disease or atrial enlargement had no effect on cardioversion characteristics or ability to restore SR. Median duration of SR following cardioversion and treatment with amiodarone was 120 days. Dogs with lone AF remained in SR longer than those with heart disease.
Biphasic cardioversion is safe and effective. Although duration of SR varied, a majority of dogs remained in SR long enough to benefit.
评估双相经胸心脏复律治疗犬心房颤动（AF）的安全性、有效性及临床实用性。
犬AF通常采用心率控制而非恢复窦性心律（SR）进行治疗。然而，恢复SR具有改善心输出量和降低心室充盈压的潜在优势，与传统单相心脏复律相比，双相心脏复律的效益/风险比更佳。
动物、材料与方法：对39只采用双相经胸心脏复律治疗的自发性AF犬的数据进行回顾性分析。评估复律特征、不良反应及SR持续时间。还评估了心脏病和胺碘酮预处理对复律成功率及SR持续时间的影响。
39只犬中有36只（92.3%）实现了SR恢复。心脏病或心房增大的存在对复律特征或恢复SR的能力无影响。复律并使用胺碘酮治疗后，SR的中位持续时间为120天。孤立性AF犬维持SR的时间比患有心脏病的犬更长。
双相心脏复律安全有效。尽管SR持续时间各异，但大多数犬维持SR的时间足以从中获益。
