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克罗地亚(巴亚什)罗姆人的Y染色体短串联重复序列(Y-STR)基因多样性

Y-STR genetic diversity of Croatian (Bayash) Roma.

作者信息

Pokupcić Kristina, Cukrov Slavena, Klarić Irena Martinović, Salihović Marijana Pericić, Lauc Lovorka Barać, Blazanović Anto, Janićijević Branka

机构信息

Forensic Centre Ivan Vucetić, General Police Directorate, Ministry of the Interior of the Republic of Croatia, Ilica 335, Zagreb, Croatia.

出版信息

Forensic Sci Int Genet. 2008 Mar;2(2):e11-3. doi: 10.1016/j.fsigen.2007.11.002.

Abstract

Seventeen Y-chromosomal short tandem repeats (STRs) (DYS19, DYS385, DYS389I, DYS398II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATA H4.1) were typed in DNA samples from 146 unrelated adult Romani Bayash men from eastern and northwestern Croatia. Analysed Croatian Bayash Romani population represents an example of genetically homogenous population characterised by low levels of haplotype diversity and unique haplotype ratio as well as sharing of the same most frequent (founding) haplotype and its close derivatives by more than one third of the analyzed men. Despite almost exclusive sharing of the same minimal haplotype and its closely related derivates on the background of the Indian Y SNP haplogroup H1, we observed considerable level of genetic differentiation of Romani populations across Europe that should not be neglected in forensic statistics.

摘要

对来自克罗地亚东部和西北部的146名不相关的成年罗姆族巴亚什男性的DNA样本进行了17个Y染色体短串联重复序列(STRs)(DYS19、DYS385、DYS389I、DYS398II、DYS390、DYS391、DYS392、DYS393、DYS437、DYS438、DYS439、DYS448、DYS456、DYS458、DYS635、GATA H4.1)分型。分析的克罗地亚巴亚什罗姆族群体代表了一个基因同质群体的例子,其特征是单倍型多样性水平低、独特的单倍型比例,以及超过三分之一的被分析男性共享相同的最常见(奠基)单倍型及其密切衍生物。尽管在印度Y单核苷酸多态性单倍群H1的背景下,几乎完全共享相同的最小单倍型及其密切相关的衍生物,但我们观察到欧洲罗姆族群体存在相当程度的遗传分化,这在法医统计学中不应被忽视。

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