Nehme Jade, Décarie Jean-Claude, Saliba Issam
Otorhinolaryngology Department, Centre Hospitalier Universitaire Sainte-Justine (CHU SJ), Montreal University, Montréal, Quebec, Canada.
Int J Pediatr Otorhinolaryngol. 2009 May;73(5):629-35. doi: 10.1016/j.ijporl.2008.10.025. Epub 2008 Dec 11.
Our review aims: (1) to highlight the suspicion of lateral sinus thrombosis (LST) following a minor head injury in the pediatric population; (2) to discuss the different etiologies of lateral sinus thrombosis; (3) to identify an exact mechanism of the thrombus formation; (4) to clarify the role of each diagnostic tool; (5) to implement an algorithm for the treatment of LST due to a minor head injury.
We performed a MEDLINE search for LST following a minor head trauma related articles that were published between 1950 and June 2008. We identified 19 related studies of which 22 patient records were noted. We also added our case to this series. The information from the reports was analyzed to characterize the clinical aspects, the radiologic findings, the treatment, the follow-up, and the management of this disease.
Twenty-three cases (20 pediatrics and 3 adults) of LST following a minor head trauma have been published including the new one presented here. The mean pediatric age in this series is 7.8 years. There were 11 cases on the right side and 8 on the left side. Male to female ratio is 1.4:1. Side and sex were not reported in 4 and 6 cases, respectively. Sigmoid and transverse sinuses were the most affected one. Eighty-three percent were treated by observation while the remaining 17% received anticoagulation. The outcome was good in all patients without any notable major complications. The radiological investigation showed that there was a complete recanalization in 9 patients and a partial recanalization in 3 patients with a mean time of 8.3 weeks.
Lateral sinus thrombosis seldomly occurs following a minor head injury. This entity is difficult to diagnose and one should exercise a high degree of suspicion when confronted with an ambiguous neurological status following a closed head trauma. The most accurate imaging test according to our experience is a multiple detector row computerized tomography (MDCT) venography completed at the time of the presentation. The indication to proceed with an MRI has to be assessed on a case-by-case basis. Anticoagulation is reserved for patients presenting a papilledema or for patients complaining of persistent headaches, vomiting, or disequilibrium.
我们的综述旨在:(1)强调小儿群体中轻微头部损伤后发生外侧窦血栓形成(LST)的可疑情况;(2)讨论外侧窦血栓形成的不同病因;(3)确定血栓形成的确切机制;(4)阐明每种诊断工具的作用;(5)实施针对轻微头部损伤所致LST的治疗算法。
我们在MEDLINE上搜索了1950年至2008年6月期间发表的与轻微头部创伤后LST相关的文章。我们确定了19项相关研究,其中记录了22例患者的情况。我们还将我们的病例纳入了该系列。对报告中的信息进行分析,以描述该疾病的临床特征、影像学表现、治疗、随访及管理情况。
已发表了23例(20例小儿和3例成人)轻微头部创伤后发生LST的病例,包括此处呈现的新病例。该系列中小儿的平均年龄为7.8岁。右侧有11例,左侧有8例。男女比例为1.4:1。分别有4例和6例未报告侧别和性别。乙状窦和横窦是受影响最严重的部位。83%的患者接受观察治疗,其余17%接受抗凝治疗。所有患者预后良好,无任何明显的严重并发症。影像学检查显示,9例患者完全再通,3例患者部分再通,平均时间为8.3周。
轻微头部损伤后很少发生外侧窦血栓形成。该病症难以诊断,当闭合性头部创伤后出现不明原因的神经状态时,应高度怀疑。根据我们的经验,最准确的影像学检查是在就诊时完成的多排探测器计算机断层扫描(MDCT)静脉造影。是否进行MRI检查必须逐案评估。抗凝治疗适用于出现视乳头水肿的患者或主诉持续性头痛、呕吐或平衡失调的患者。