Deng Chunyan, Chen Jinhua, Wang Mengdong, Xiao Chunhui, Nie Zhou, Yao Shouzhuo
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
Biosens Bioelectron. 2009 Mar 15;24(7):2091-4. doi: 10.1016/j.bios.2008.10.022. Epub 2008 Nov 6.
The Boron-doped carbon nanotubes (BCNTs) modified glassy carbon (GC) electrode was obtained simply and used for highly selective and sensitive determination of dopamine (DA). Comparing with the bare GC and CNTs/GC electrodes, the BCNTs have higher catalytic activity toward the oxidation of DA and ascorbic acid (AA). Moreover, the voltammetric peaks of AA and DA were separated enough (ca. 238 mV) at the BCNTs/GC electrode, which is superior to that at the CNTs/GC electrode (ca. 122 mV). Thus, the selective determination of DA was carried out successfully in the presence of AA. A wide concentration range (2.0 x 10(-8)-7.5 x 10(-5)M) and low detection limit (1.4 nM, S/N=3) for the DA detection were obtained. The possibility of the BCNTs/GC electrode for the determination of DA in human blood serum has also been evaluated. The advantageous properties of this electrode for the DA determination lie in its excellent catalytic activity, selectivity and simplicity. The more edge plane sites presented on the BCNTs surface were partially responsible for its good analytical behavior.
硼掺杂碳纳米管（BCNTs）修饰玻碳（GC）电极的制备方法简便，并用于多巴胺（DA）的高选择性和高灵敏度测定。与裸玻碳电极和碳纳米管/玻碳电极相比，硼掺杂碳纳米管对多巴胺和抗坏血酸（AA）的氧化具有更高的催化活性。此外，在硼掺杂碳纳米管/玻碳电极上，抗坏血酸和多巴胺的伏安峰分离得足够远（约238 mV），优于碳纳米管/玻碳电极（约122 mV）。因此，在存在抗坏血酸的情况下成功实现了多巴胺的选择性测定。获得了宽浓度范围（2.0×10⁻⁸ - ⁷.⁵×10⁻⁵ M）的多巴胺检测结果以及低检测限（1.4 nM，S/N = 3）。还评估了硼掺杂碳纳米管/玻碳电极用于测定人血清中多巴胺的可能性。该电极用于多巴胺测定的优势特性在于其优异的催化活性、选择性和简便性。硼掺杂碳纳米管表面呈现的更多边缘平面位点部分地促成了其良好的分析性能。
