Michota Franklin A, Amin Alpesh
Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.
J Hosp Med. 2008 Nov;3(6 Suppl):S7-15. doi: 10.1002/jhm.395.
Registry data indicate a gap between evidence-based guidelines and current management of patients with acute decompensated heart failure (ADHF). Bridging this gap is crucial given the frequency and cost of hospitalization for this disorder. Patients with ADHF require rapid assessment to determine appropriate treatment location and initial therapy. Patients with impending respiratory failure or cardiogenic shock should be managed in an intensive care setting, patients with congestion that is expected to require prolonged intravenous therapy should be admitted to the hospital, and patients with congestion that is likely to respond within 12-24 hours can be managed in an observation unit. Clinical status should guide selection of initial therapy. Initially, therapeutic response should be assessed every couple of hours. Once effective acute therapy has been established, it is important to implement strategies to improve long-term outcomes. These strategies include ensuring that care complies with established core performance measures, providing patient education in a manner suited to ensure comprehension and retention, and arranging for appropriate outpatient follow-up, ideally in a comprehensive heart failure disease management program. The purpose of this review is (1) to examine evidence-based guidelines for the treatment of ADHF, (2) to present a practical algorithm for patient assessment and treatment derived from these guidelines and personal experience, and (3) to discuss systems to enhance the ultimate transition of patient care from the inpatient to outpatient setting.
登记数据显示,急性失代偿性心力衰竭(ADHF)患者的循证指南与当前治疗之间存在差距。鉴于该疾病的住院频率和费用,弥合这一差距至关重要。ADHF患者需要迅速评估,以确定合适的治疗地点和初始治疗方案。即将发生呼吸衰竭或心源性休克的患者应在重症监护环境中进行治疗,预计需要长期静脉治疗的充血性患者应入院治疗,而可能在12 - 24小时内有反应的充血性患者可在观察病房进行治疗。临床状况应指导初始治疗的选择。最初,应每隔几个小时评估一次治疗反应。一旦确立了有效的急性治疗方案,实施改善长期预后的策略就很重要。这些策略包括确保治疗符合既定的核心绩效指标,以确保理解和记忆的方式提供患者教育,并安排适当的门诊随访,理想情况下是在全面的心力衰竭疾病管理计划中进行。本综述的目的是:(1)研究ADHF治疗的循证指南;(2)根据这些指南和个人经验,提出一种实用的患者评估和治疗算法;(3)讨论加强患者护理从住院到门诊最终过渡的系统。