Mirra M, Vitulano G, Virtuoso N, Tufano N, D'Auria F, De Angelis S, Giudice R, Lambiase A, Gigantino A, Piscione F
Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
Department of Emergency, University Hospital of Salerno, Salerno, Italy.
Transl Med UniSa. 2014 Dec 19;11:59-62. eCollection 2015 Jan-Apr.
Incidence of chronic heart failure (HF) is rapidly increasing, approaching a 10 per 1000 rate after 65 years of age. In the last decades, despite pharmacological, interventional and supportive innovations, HF prognosis remained poor, with about 30% of death within one year from the diagnosis. Current guidelines recommend for these patients management programs providing follow-up through dedicated outpatient clinic. Limits of these programs are represented by great difficulties in getting patients adherence, being still too elevated the rate of abandonments. In this paper, we analyzed the impact of 58 months of activity in our dedicated to heart failure outpatient clinic on mortality, hospitalization and abandonment rate. 477 HF patients (346 M, 72.5%, mean age 69.6 years) were enrolled. Mean follow-up and visit were 18.2 and 2.6 months respectively. Total mortality rate was 11.5%, 4% of patients per year. Total hospitalizations for acute HF were 212 and, among all patients left in follow-up, the number of hospitalizations for acute de-compensation significantly decreased from 0.49/patient/year before enrollment to 0.29/patient/year during follow-up (p=0.015). Patients who abandoned outpatient clinic were 94 (19%, 1 abandonment every 23 days), mostly observed over the first months of activity. In conclusion, our patients experienced a major decrease in rates of acute de-compensation and need of in-hospital admissions.
慢性心力衰竭(HF)的发病率正在迅速上升,65岁以后接近千分之十的比率。在过去几十年中,尽管在药物治疗、介入治疗和支持治疗方面有所创新,但HF的预后仍然很差,诊断后一年内约有30%的患者死亡。当前指南建议为这些患者提供通过专门门诊进行随访的管理方案。这些方案的局限性在于患者依从性方面存在很大困难,放弃治疗的比率仍然过高。在本文中,我们分析了我们专门的心力衰竭门诊58个月的活动对死亡率、住院率和放弃治疗率的影响。纳入了477例HF患者(男性346例,占72.5%,平均年龄69.6岁)。平均随访时间和就诊次数分别为18.2个月和2.6次。总死亡率为11.5%,即每年4%的患者。急性HF的总住院次数为212次,在所有接受随访的患者中,急性失代偿的住院次数从入组前的0.49次/患者/年显著降至随访期间的0.29次/患者/年(p = 0.015)。放弃门诊治疗的患者有94例(19%,每23天有1例放弃),主要出现在活动的前几个月。总之,我们的患者急性失代偿率和住院需求率大幅下降。