Dinis-Ribeiro Mario, Correia Ricardo, Santos Cristina, Fernandes Sonia, Palhares Ernesto, Silva Rui-Almeida, Amaro Pedro, Areia Miguel, Costa-Pereira Altamiro, Moreira-Dias Luis
Gastroenterology Department, Portuguese Oncology Institute, Porto 4200-072, Portugal.
World J Gastroenterol. 2008 Dec 14;14(46):7086-92. doi: 10.3748/wjg.14.7086.
To evaluate the use of web-based technologies to assess the learning curve and reassess reproducibility of a simplified version of a classification for gastric magnification chromoendoscopy (MC).
As part of a multicenter trial, a hybrid approach was taken using a CD-ROM, with 20 films of MC lasting 5 s each and an "autorun" file triggering a local HTML frameset referenced to a remote questionnaire through an Internet connection. Three endoscopists were asked to prospectively and independently classify 10 of these films randomly selected with at least 3 d apart. The answers were centrally stored and returned to participants together with adequate feedback with the right answer.
For classification in 3 groups, both intra- [Cohen's kappa (kappa) = 0.79-1.00 to 0.89-1.00] and inter-observer agreement increased from 1st (moderate) to 6th observation (kappa = 0.94). Also, agreement with reference increased in the last observations (0.90, 1.00 and 1.00, for observers A, B and C, respectively). Validity of 100% was obtained by all observers at their 4th observation. When a 4th (sub)group was considered, inter-observer agreement was almost perfect (kappa = 0.92) at 6th observation. The relation with reference clearly improved into kappa (0.93-1.00) and sensitivity (75%-100%) at their 6th observations.
This MC classification seems to be easily explainable and learnable as shown by excellent intra- and inter-observer agreement, and improved agreement with reference. A web system such as the one used in this study may be useful for endoscopic or other image based diagnostic procedures with respect to definition, education and dissemination.
评估利用基于网络的技术来评估胃放大染色内镜检查(MC)简化版分类的学习曲线并重新评估其可重复性。
作为一项多中心试验的一部分,采用了一种混合方法,使用一张光盘,其中包含20段时长均为5秒的MC影片以及一个“自动运行”文件,该文件通过互联网连接触发一个指向远程问卷的本地HTML框架集。三名内镜医师被要求前瞻性地、独立地对随机选择的10段影片进行分类,且分类时间间隔至少为3天。答案集中存储,并将正确答案及适当反馈一同返回给参与者。
对于分为3组的分类,组内一致性[科恩kappa系数(kappa)=0.79 - 1.00至0.89 - 1.00]和观察者间一致性从第1次观察(中等)到第6次观察均有所提高(kappa = 0.94)。此外,在最后几次观察中与参考标准的一致性也有所提高(观察者A、B和C分别为0.90、1.00和1.00)。所有观察者在第4次观察时均达到了100%的有效性。当考虑第4个(亚)组时,观察者间一致性在第6次观察时几乎达到完美(kappa = 0.92)。在第6次观察时,与参考标准的关系明显改善,kappa值为0.93 - 1.00,敏感度为75% - 100%。
如观察者内和观察者间的出色一致性以及与参考标准的改善一致性所示,这种MC分类似乎易于解释和学习。本研究中使用的此类网络系统可能有助于内镜或其他基于图像的诊断程序的定义、培训和传播。