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老年女性肝脏未分化胚胎性肉瘤:病例报告及文献复习

Undifferentiated embryonal sarcoma of liver in an old female: case report and review of the literature.

作者信息

Ma Li, Liu Yue-Ping, Geng Cui-Zhi, Tian Zhi-Hui, Wu Guo-Xiang, Wang Xiao-Ling

机构信息

Department of Surgery, Forth Hospital of Hebei Medical University, No. 12, Jiankang Road, Shijiazhuang 050011, Hebei Province, China.

出版信息

World J Gastroenterol. 2008 Dec 21;14(47):7267-70. doi: 10.3748/wjg.14.7267.

Abstract

The clinical characteristics of undifferentiated (embryonal) sarcoma of the liver (UESL) were investigated and the best treatment modalities were recommended. Both histology and immuno-histochemistry demonstrated the cellular features of this peculiar tumor. The tumor size was 12 cm multiply 9 cm multiply 8 cm in the right liver lobe. The patient underwent surgical resection of the tumor. The postoperative recovery was uneventful and she died eight months after diagnosis. The tumor showed mixed spindle and polygonal cells within the myxoid matrix. Some tumor cells contained eosinophilic hyaline globules that were positive for resistant diastase. Immunohistochemistry showed positive vimentin. Stellate and spindle cells were positively stained with alpha-1-antichymotrypsin (AACT) and CD68. This case indicates that UESL is not obviously differentiated in old-aged adults.

摘要

对肝未分化(胚胎性)肉瘤(UESL)的临床特征进行了研究,并推荐了最佳治疗方式。组织学和免疫组织化学均显示了这种特殊肿瘤的细胞特征。肿瘤位于右肝叶,大小为12厘米×9厘米×8厘米。患者接受了肿瘤手术切除。术后恢复顺利,诊断后八个月死亡。肿瘤在黏液样基质内显示出梭形和多角形细胞混合。一些肿瘤细胞含有对耐淀粉酶呈阳性的嗜酸性透明小球。免疫组织化学显示波形蛋白呈阳性。星状细胞和梭形细胞用α-1-抗糜蛋白酶(AACT)和CD68呈阳性染色。该病例表明,UESL在老年成年人中分化不明显。

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