Motoyama Osamu, Sugawara Hidenori, Hatano Michihiro, Fujisawa Tomoo, Iitaka Kikuo
Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura-shi, Chiba, 285-8741, Japan.
Department of Pediatrics, Saiseikai Yokohama-shi Tobu Hospital, Kanagawa, Japan.
Clin Exp Nephrol. 2009 Apr;13(2):170-173. doi: 10.1007/s10157-008-0117-7. Epub 2008 Dec 16.
Few reports of familial cases of steroid-sensitive nephrotic syndrome (SSNS) are available. Of 123 children with SSNS, four cases in two families are presented. Two sisters and a father and his daughter developed SSNS. The incidence of SSNS siblings in Japan seems to be similar to the incidence reported in other countries. SSNS in two generations is rare. To our knowledge, cases of SSNS in a parent and a child in Japan have not been reported.
关于类固醇敏感性肾病综合征(SSNS)家族病例的报道很少。在123例SSNS患儿中,呈现了两个家族中的4例。两名姐妹以及一名父亲和他的女儿患上了SSNS。在日本,SSNS患儿兄弟姐妹的发病率似乎与其他国家报道的发病率相似。两代人都患SSNS的情况很罕见。据我们所知,日本尚未报道过父母与子女均患SSNS的病例。