Tsiridis Eleftherios, Velonis Stylianos, Limb David, Giannoudis Peter V
Academic Department of Trauma and Orthopaedic Surgery, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, School of Medicine, Leeds University, Leeds, United Kingdom.
Connect Tissue Res. 2008;49(6):455-63. doi: 10.1080/03008200802325383.
Tissue engineering is an emerging scientific approach that may offer alternative pathways for managing tissue degeneration. The use of cellular and acellular matrix in combination with cells and/or growth factors is one approach currently being explored in the management of rotator cuff disease. Interestingly, the integration of gene therapy with this technique introduces a new dimension to treatment options. The scope of this article is to present an overview of the current tissue engineering in vivo methods being clinically investigated in rotator cuff disease.
组织工程是一种新兴的科学方法，可能为处理组织退变提供替代途径。将细胞和无细胞基质与细胞和/或生长因子结合使用是目前在肩袖疾病管理中正在探索的一种方法。有趣的是，基因治疗与该技术的整合为治疗选择引入了一个新的维度。本文的范围是概述目前正在临床研究的用于肩袖疾病的体内组织工程方法。
