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发展中国家止血与血栓形成的分子遗传学检测:成就、希望与挑战

Molecular genetic testing of hemostasis and thrombosis in developing countries: achievements, hopes, and challenges.

作者信息

Ozelo Margareth Castro, Zapata Esp Roman, Qadura Mohammad, Chegeni Rouzbeh, Othman Maha

机构信息

Hemocentro da UNICAMP, Campinas, Brazil.

出版信息

Semin Thromb Hemost. 2008 Sep;34(6):569-78. doi: 10.1055/s-0028-1103368. Epub 2008 Nov 28.

Abstract

In today's developing world, how do we define a "developing country"? What level of effort and resources is invested in diagnosis, patient care, and research in those countries that we define to be developing? In particular, what is the situation with respect to molecular genetic testing in these countries? How much has been achieved to date, and what are the challenges to further achievements? This article describes the current status, challenges, and future hopes with respect to molecular genetic testing in hemostasis and thrombosis from the perspective of experts from three countries: Brazil, Colombia, and Iran. These individuals have lived and practiced genetic testing in their countries and have also had the experience to work and/or interact with the developed world to enable an appreciation of the difference.

摘要

在当今发展中的世界,我们如何定义一个“发展中国家”?在我们定义为发展中国家的那些国家,在诊断、患者护理和研究方面投入了何种程度的努力和资源?特别是,这些国家在分子基因检测方面的情况如何?迄今为止取得了哪些成果,进一步取得成果面临哪些挑战?本文从巴西、哥伦比亚和伊朗这三个国家的专家视角,描述了止血和血栓形成方面分子基因检测的现状、挑战及未来期望。这些人在他们自己的国家从事基因检测工作,也有与发达国家合作和/或互动的经历,从而能够认识到其中的差异。

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