Daubner D, Prokosch V, Busse H, Stupp T
Universitätsaugenklinik, Universität Münster.
Klin Monbl Augenheilkd. 2008 Dec;225(12):1045-50. doi: 10.1055/s-2008-1027609. Epub 2008 Dec 15.
The aim of this study was to evaluate the long-term survival rate and functional results after iridocyclectomy.
Between 1980 and 2002 39 patients (26 female and 13 male) ranging in age from 20 to 79 years (median m = 58 years) underwent iridocyclectomy for a tumour of periphery iris by means of a lamellar technique or by trepanating. Follow-up time ranged from 3 months to 24 years (m = 11.2 years).
In 21 cases (54 %) there was a malignant tumour including 20 melanomas (mostly spindle-cell and mixed-cell melanomas) and one filiae of a bronchial carcinoma. There was a variety of histopathological entities in the 18 benign lesions (46 %). Naevi were the most frequent. The outcome was satisfactory: 57 % of the patients kept a visual acuity of > 0.5. Three eyes had to be enucleated. The rate of recurrence was 10 % (4 cases). The Kaplan-Meyer estimate for the 10-year-survival of the patients with a malignant iris tumour was 77 %. Two patients died of metastic melanoma following spindle-cell and mixed-cell melanoma.
The long-term functional results after Iridocyclectomy are good, whereas complications and recurrences are rare. The 10-year-survival is high. Over a long period iridocyclectomy is a recommendable surgical procedure for removal of progredient tumours of the anterior uvea.
本研究的目的是评估虹膜睫状体切除术的长期生存率和功能结果。
1980年至2002年间，39例患者（26例女性和13例男性），年龄在20至79岁之间（中位年龄m = 58岁），通过板层技术或环钻术对周边虹膜肿瘤进行了虹膜睫状体切除术。随访时间为3个月至24年（m = 11.2年）。
21例（54%）为恶性肿瘤，包括20例黑色素瘤（主要为梭形细胞和混合细胞黑色素瘤）和1例支气管癌转移灶。18例良性病变（46%）有多种组织病理学类型。痣最为常见。结果令人满意：57%的患者视力保持在> 0.5。3只眼不得不摘除眼球。复发率为10%（4例）。恶性虹膜肿瘤患者10年生存率的Kaplan - Meyer估计值为77%。2例患者死于梭形细胞和混合细胞黑色素瘤的转移性黑色素瘤。
虹膜睫状体切除术后的长期功能结果良好，而并发症和复发很少见。10年生存率很高。长期来看，虹膜睫状体切除术是切除前部葡萄膜进行性肿瘤的一种值得推荐的手术方法。
