Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosing.
作者信息
Nantermet Philippe G, Rajapakse Hemaka A, Stanton Mathew G, Stauffer Shaun R, Barrow James C, Gregro Allison R, Moore Keith P, Steinbeiser Melissa A, Swestock John, Selnick Harold G, Graham Samuel L, McGaughey Georgia B, Colussi Dennis, Lai Ming-Tain, Sankaranarayanan Sethu, Simon Adam J, Munshi Sanjeev, Cook Jacquelynn J, Holahan Marie A, Michener Maria S, Vacca Joseph P
机构信息
Department of Medicinal Chemistry, Merck Research Laboratories, P.O Box 4, WP14-3, West Point, PA 19486, USA.
出版信息
ChemMedChem. 2009 Jan;4(1):37-40. doi: 10.1002/cmdc.200800308.
PMID:19085994
Abstract
摘要
Zotero 插件