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刚抵达大加那利岛(西班牙)的撒哈拉以南移民中幽门螺杆菌和细胞毒素相关基因A血清流行率

Helicobacter pylori and cagA seroprevalence in sub-Saharan inmigrants recently arrived to Gran Canaria (Spain).

作者信息

Sanz-Peláez Oscar, Santana-Rodríguez Evora, Maroto Alfonso Angel-Moreno, Carranza-Rodríguez Cristina, Pisos-Alamo Elena, Pérez-Arellano José-Luis

机构信息

Sevicio de Medicina Interna, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.

出版信息

Scand J Infect Dis. 2008;40(9):756-8. doi: 10.1080/00365540801995378.

Abstract

Non-ulcerous dyspepsia is common among sub-Saharan people migrating into Spain. Given the high prevalence of H. pylori (HP) infection in their countries of origin, we studied the prevalence of infection in this population, and specifically the prevalence of infection by the more virulent, cagA-positive strains (CAP). 140 sub-Saharan immigrants recently arrived to Gran Canaria (Canary Islands, Spain) were studied. 80.7% were male, with a mean age of 24.2 y. 90.7% tested seropositive for HP and 72.2% of them carried antibodies against the 'pathogenicity island' cagA. We did not find any relationship between the presence of these antibodies and the clinical variables studied. We can conclude that HP infection is virtually universal in this population, with a high percentage of infection by CAP strains.

摘要

非溃疡性消化不良在撒哈拉以南地区移民到西班牙的人群中很常见。鉴于他们原籍国幽门螺杆菌(HP)感染的高患病率,我们研究了该人群中的感染患病率,特别是更具毒性的细胞毒素相关基因A阳性菌株(CAP)的感染患病率。我们对140名最近抵达大加那利岛(西班牙加那利群岛)的撒哈拉以南移民进行了研究。其中80.7%为男性,平均年龄24.2岁。90.7%的人HP血清学检测呈阳性,其中72.2%携带针对“致病岛”cagA的抗体。我们没有发现这些抗体的存在与所研究的临床变量之间存在任何关系。我们可以得出结论,HP感染在该人群中几乎普遍存在,CAP菌株感染的比例很高。

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