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伴有N2淋巴结转移的IIIA期非小细胞肺癌的管理算法

Management algorithms for stage IIIA non-small cell lung cancer with N2 node involvement.

作者信息

Detterbeck Frank, Sukumar Mithran S

机构信息

Department of Surgery, Section of Thoracic Surgery, Yale University, 333 Cedar Street, FMB 128, P.O. Box 208062, New Haven, CT 06520, USA.

出版信息

Thorac Surg Clin. 2008 Nov;18(4):437-41, vii. doi: 10.1016/j.thorsurg.2008.08.006.

DOI:10.1016/j.thorsurg.2008.08.006
PMID:19086612
Abstract

Stage IIIA non-small cell lung cancer (NSCLC) with N2 node involvement (IIIA[N2]) is a complex area characterized by much confusion and controversy, because data derived from a particular subgroup of IIIA(N2) often are inappropriately applied to another subgroup. The problem is not so much that stage IIIA(N2) encompasses a spectrum of disease, which is true in each stage of NSCLC. Rather, our ability to describe a patient cohort has been limited, and it is therefore often difficult to determine how and when to apply data from published studies. A simple, pragmatic approach is taken in this article to define algorithms for the management of these patients.

摘要

伴有N2淋巴结转移的IIIA期非小细胞肺癌(NSCLC,IIIA[N2])是一个复杂的领域,存在诸多混淆和争议,因为来自IIIA(N2)特定亚组的数据常常被不适当地应用于另一个亚组。问题并不在于IIIA(N2)涵盖了一系列疾病,这在NSCLC的每个阶段都是如此。相反,我们描述患者队列的能力有限,因此往往难以确定如何以及何时应用已发表研究的数据。本文采用一种简单、实用的方法来定义这些患者的管理算法。

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