Suga T, Takahashi Y, Ogino T, Mai M
Dept. of Surgery, Cancer Research Institute, Kanazawa University.
Gan To Kagaku Ryoho. 1991 Aug;18(11):1962-4.
Both arterial infusion chemotherapy and biochemical modulation are effective for unresectable and recurrent cancer patients. Thus, we tried to combine these methods and studied their combined efficacy in 30 cancer patients. Overall effectiveness was 40% with this method. The efficacy of each regimen, such as beta-MF and CF, was approximately 36.4% and 66.7%, respectively. The effectiveness of cannulation into the proper hepatic artery and aorta was 48.6% and 16.7%, respectively. In this study, there were no serial or severe side effects. These findings suggested that arterial infusion chemotherapy in combination with biochemical modulation was a safe and effective method for treating cancer patients.
动脉灌注化疗和生化调节对无法切除的复发性癌症患者均有效。因此，我们尝试将这两种方法结合，并在30例癌症患者中研究了它们的联合疗效。采用这种方法的总体有效率为40%。每种方案的疗效，如β-丙氨酸和亚叶酸，分别约为36.4%和66.7%。经适当肝动脉和主动脉插管的有效率分别为48.6%和16.7%。在本研究中，未出现连续或严重的副作用。这些发现表明，动脉灌注化疗联合生化调节是治疗癌症患者的一种安全有效的方法。
