[山药多糖 - 铁（III）配合物的组成与性质表征]
[Composition and property characterization of Rhizoma Dioscoreae polysaccharide-Fe (III) complex].
作者信息
Li Ming-jing, Yang Jing, Wang Ning, Wang Yong, Liu Xiu-hua
机构信息
Key Lab of Natural Drug and Immune Engineering, College of Chemistry and Chemical Engineering Henan University, Kaifeng 475001, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):2002-5.
OBJECTIVE
To characterize properties of Rhizoma Dioscoreae polysaccharide-Fe (III) complex (RDPC) and analyze its composition.
METHOD
Physicochemical properties, such as character, solubility and stability of RDPC were studied. Surface structure of RDPC was studied by Infrared spectroscopic technique and transmission electron microscopy. The content of Fe (III) in RDPC was determined by o-phenanthroline spectrophotometry after being treated by ashing, wet digestion, or direct dissolution methods. Content of polysaccharide in RDPC was determined by sulphuric acid-phenol method.
RESULT
RDPC was brownish red powder. It could dissolve in water, its aqueous solution was very stable at the pH from 3.8 to 11.6. RDPC was a surface complex in which polysaccharide combined with beta-FeOOH as core. The content of Fe (III) in RDPC was 17.05%, 16.53%, 17.10% respectively after being treated by 3 different pretreatment methods. Content of polysaccharide in RDPC was 16.27%.
CONCLUSION
This is the first report of RDPC which was stable under physiological pH conditions and could be a new candidate for iron-supplementary.
目的
表征山药多糖 - 铁（III）配合物（RDPC）的性质并分析其组成。
方法
研究RDPC的物理化学性质，如性状、溶解性和稳定性。通过红外光谱技术和透射电子显微镜研究RDPC的表面结构。采用灰化、湿法消解或直接溶解法处理后，用邻菲罗啉分光光度法测定RDPC中铁（III）的含量。用硫酸 - 苯酚法测定RDPC中多糖的含量。
结果
RDPC为棕红色粉末。它可溶于水，其水溶液在pH值3.8至11.6范围内非常稳定。RDPC是一种表面配合物，其中多糖与β - FeOOH作为核心结合。经3种不同预处理方法处理后，RDPC中铁（III）的含量分别为17.05%、16.53%、17.10%。RDPC中多糖的含量为16.27%。
结论
这是关于RDPC的首次报道，其在生理pH条件下稳定，可能是一种新型补铁剂。
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